PGRMC1 and CCDC134

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PGRMC1	CCDC134
Description		progesterone receptor membrane component 1	coiled-coil domain containing 134
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Endomembrane System Membrane Smooth Endoplasmic Reticulum Membrane Specific Granule Membrane Neuron Projection Neuronal Cell Body Cell Body Synapse	Extracellular Region Nucleus Endoplasmic Reticulum Membrane
	Molecular Function	Amyloid-beta Binding Steroid Binding Protein Binding Heme Binding Protein Homodimerization Activity Metal Ion Binding	Protein Binding
	Biological Process	Heme Biosynthetic Process	Angiogenesis Placenta Development Ventricular System Development Embryonic Hemopoiesis Embryonic Liver Development
Pathways		Neutrophil degranulation
Drugs		Dextromethorphan Nortriptyline Sertraline
Diseases
GWAS		Hodgkin's lymphoma ( 34216518)	Alanine aminotransferase levels ( 33547301) Alzheimer's disease biomarkers ( 21123754) Intelligence (MTAG) ( 29326435) Meat-related diet ( 32066663) Plateletcrit ( 32888494) Processed meat consumption ( 32066663) Refractive error ( 32231278)
Interacting Genes		21 interacting genes: BIK CAMLG CCDC134 CENPU CIAO1 CREB3L1 DEFB124 EVI2B GET3 GLP1R GOLM1 KASH5 KCNE5 MTNR1A MX1 PAM16 PGRMC2 SCAP SGTB TMEM213 ZNF71	5 interacting genes: CENPM PGRMC1 PTPRN TADA2A UBQLN4
Entrez ID		10857	79879
HPRD ID		02338	07988
Ensembl ID		ENSG00000101856	ENSG00000100147
Uniprot IDs		O00264 Q6IB11	B0QY51 B4DRL0 Q9H6E4
PDB IDs		4X8Y
Enriched GO Terms of Interacting Partners?
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