RUVBL2 and DPCD

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
HPRD (two hybrid)

		RUVBL2	DPCD
Description		RuvB like AAA ATPase 2	deleted in primary ciliary dyskinesia homolog (mouse)
Image			No pdb structure
GO Annotations	Cellular Component	Euchromatin Swr1 Complex Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Membrane Nuclear Matrix Ino80 Complex NuA4 Histone Acetyltransferase Complex Extracellular Exosome MLL1 Complex R2TP Complex Dynein Axonemal Particle Ribonucleoprotein Complex	Extracellular Region Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding TFIID-class Transcription Factor Complex Binding DNA Helicase Activity Transcription Corepressor Activity Protein Binding ATP Binding Beta-catenin Binding ATP Hydrolysis Activity TBP-class Protein Binding Chromatin DNA Binding Identical Protein Binding Protein Homodimerization Activity 5'-3' DNA Helicase Activity ADP Binding Unfolded Protein Binding ATPase Binding Promoter-enhancer Loop Anchoring Activity	Protein Binding
	Biological Process	Box C/D SnoRNP Assembly DNA Repair DNA Recombination Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Protein Folding Histone Acetylation DNA Duplex Unwinding Cellular Response To UV Positive Regulation Of Histone Acetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Establishment Of Protein Localization To Chromatin Cellular Response To Estradiol Stimulus Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Telomerase RNA Localization To Cajal Body	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Spermatogenesis Determination Of Left/right Symmetry Lateral Ventricle Development Third Ventricle Development Flagellated Sperm Motility Left/right Pattern Formation
Pathways		Telomere Extension By Telomerase HATs acetylate histones
Drugs		Quercetin
Diseases
GWAS		Blood protein levels ( 28240269)	Mean corpuscular volume ( 32888494)
Interacting Genes		33 interacting genes: AGR2 APP APPL1 APPL2 ATF2 BCL3 CCDC103 CDKN2A CTNNB1 DNAJB4 DPCD EHMT2 EP300 EXOSC10 FBL FDFT1 HDAC1 HDAC4 LIG4 LNX1 MCPH1 MDM2 MYC NDRG1 OGT RUVBL1 STOM TAF9 TBP TERT TXNIP YWHAQ YY1	13 interacting genes: ACTR1A APP BTRC CNNM2 CUEDC2 GUCA2B HACD3 MNDA NDUFS7 NOLC1 PPRC1 RUVBL2 WBP1L
Entrez ID		10856	25911
HPRD ID		16070	13247
Ensembl ID		ENSG00000183207	ENSG00000166171
Uniprot IDs		B3KNL2 Q9Y230	Q5JQQ4 Q9BVM2
PDB IDs		2CQA 2XSZ 3UK6 5OAF 6FO1 6H7X 6HTS 6IGM 6K0R 6QI8 6QI9 7AHO
Enriched GO Terms of Interacting Partners?
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