DPCD and ACTR1A

		DPCD	ACTR1A
Description		deleted in primary ciliary dyskinesia homolog (mouse)	actin related protein 1A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus	Manchette Cytoplasm Centrosome Centriole Cytosol Dynactin Complex Microtubule Associated Complex Microtubule Cytoskeleton COPI-coated Vesicle Extracellular Exosome Cell Cortex Region
	Molecular Function	Protein Binding	Protein Binding ATP Binding
	Biological Process	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Spermatogenesis Determination Of Left/right Symmetry Lateral Ventricle Development Third Ventricle Development Flagellated Sperm Motility Left/right Pattern Formation	Spermatogenesis Vesicle-mediated Transport
Pathways			MHC class II antigen presentation Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic AURKA Activation by TPX2
Drugs
Diseases
GWAS		Mean corpuscular volume ( 32888494)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Hip circumference adjusted for BMI ( 34021172) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Prostate cancer ( 23535732) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		13 interacting genes: ACTR1A APP BTRC CNNM2 CUEDC2 GUCA2B HACD3 MNDA NDUFS7 NOLC1 PPRC1 RUVBL2 WBP1L	7 interacting genes: CNNM2 DCTN1 DCTN4 DPCD NUMA1 SPTBN1 SPTBN2
Entrez ID		25911	10121
HPRD ID		13247	05507
Ensembl ID		ENSG00000166171	ENSG00000138107
Uniprot IDs		Q5JQQ4 Q9BVM2	A0A384NQ21 P61163
PDB IDs
Enriched GO Terms of Interacting Partners?
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