CCR9 and CCL25

Number of citations of the paper that reports this interaction (PubMedID 10229797)
43

Data Source:
HPRD (in vivo, in vitro)

		CCR9	CCL25
Description		C-C motif chemokine receptor 9	C-C motif chemokine ligand 25
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface	Extracellular Region Extracellular Space
	Molecular Function	Chemokine Receptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding	Hormone Activity Protein Binding Chemokine Activity CCR10 Chemokine Receptor Binding Chemokine Receptor Binding CCR Chemokine Receptor Binding
	Biological Process	CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Chemotaxis Immune Response Cellular Defense Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Positive Regulation Of Cell-matrix Adhesion Monocyte Chemotaxis Chemotaxis Inflammatory Response Immune Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Cell Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Negative Regulation Of Leukocyte Tethering Or Rolling
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs		Vercirnon
Diseases
GWAS		Celiac disease ( 20190752) Liver enzyme levels (alkaline phosphatase) ( 33972514) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)	Blood protein levels ( 30072576 29875488) Metabolite levels ( 23823483) Neurocognitive impairment in HIV-1 infection (continuous) ( 28447399) Sphingolipid levels ( 26068415)
Interacting Genes		20 interacting genes: ADGRG1 AIG1 CCL25 CD81 DGAT1 G6PC3 HLA-A KDELR1 NEU1 OSTC RHBDD2 SAP130 SCAMP4 SPNS1 TMC6 TMEM33 TRPM4 TSPAN7 TTYH1 YWHAE	12 interacting genes: ACKR2 ACKR4 CCL17 CCL5 CCR10 CCR9 CXCL11 CXCL12 CXCL17 PF4 PF4V1 SMARCA4
Entrez ID		10803	6370
HPRD ID		09200	03976
Ensembl ID		ENSG00000173585	ENSG00000131142
Uniprot IDs		B2R734 P51686	O15444
PDB IDs		5LWE
Enriched GO Terms of Interacting Partners?
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