CCR9 and RHBDD2

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		CCR9	RHBDD2
Description		C-C motif chemokine receptor 9	rhomboid domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface	Golgi Membrane Hrd1p Ubiquitin Ligase ERAD-L Complex Nucleoplasm Golgi Apparatus Integral Component Of Endoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Chemokine Receptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding	Serine-type Endopeptidase Activity Misfolded Protein Binding Ubiquitin-specific Protease Binding
	Biological Process	CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Chemotaxis Immune Response Cellular Defense Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs		Vercirnon
Diseases
GWAS		Celiac disease ( 20190752) Liver enzyme levels (alkaline phosphatase) ( 33972514) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)	Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		20 interacting genes: ADGRG1 AIG1 CCL25 CD81 DGAT1 G6PC3 HLA-A KDELR1 NEU1 OSTC RHBDD2 SAP130 SCAMP4 SPNS1 TMC6 TMEM33 TRPM4 TSPAN7 TTYH1 YWHAE	58 interacting genes: ABHD16A ACSF2 ADORA2A BCL2L1 BCL2L2 CCR9 CHRM4 CIAO2A CIDEB COL8A1 COMT DIABLO DRD2 DYNC1H1 ERBB2 FKBP8 FMO4 GAL3ST3 GCSH GDF5-AS1 H2BC3 H4C7 IFI27L1 IL32 LETMD1 LIG4 MAOB MFSD14C MICOS13 MIEF2 MLX MMRN2 MPC2 MRM1 MRPL35 MTERF3 MYG1 NAALAD2 NCBP2AS2 NFU1 NRM PBX3 PTAFR ROMO1 RSAD2 SCGB3A1 SDHD SLC25A2 SLC25A3 SNPH SYT16 TEX44 THBD TIMM17B TPRG1 TSR1 TUFM USP30
Entrez ID		10803	57414
HPRD ID		09200	11492
Ensembl ID		ENSG00000173585	ENSG00000005486
Uniprot IDs		B2R734 P51686	Q6NTF9
PDB IDs		5LWE
Enriched GO Terms of Interacting Partners?
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