DRAP1 and FEZ2

Number of citations of the paper that reports this interaction (PubMedID 16484223)
20

Data Source:
BioGRID (two hybrid)

		DRAP1	FEZ2
Description		DR1 associated protein 1	fasciculation and elongation protein zeta 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Negative Cofactor 2 Complex RNA Polymerase II Transcription Regulator Complex	Cytoplasm Axon
	Molecular Function	Core Promoter Sequence-specific DNA Binding RNA Polymerase II General Transcription Initiation Factor Binding DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Identical Protein Binding Protein Heterodimerization Activity	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Signal Transduction Nervous System Development Axon Guidance Negative Regulation Of Autophagosome Assembly
Pathways		Signaling by NODAL Signaling by Activin
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Asthma ( 31959851) Eosinophil percentage of granulocytes ( 27863252) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252) Severe influenza A (H1N1) infection ( 26379185)	Apolipoprotein A1 levels ( 32203549) Haemorrhoidal disease ( 33888516) Hip circumference adjusted for BMI ( 34021172) Intraocular pressure ( 29617998) Metabolite levels ( 23823483) Offspring birth weight ( 31043758) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		31 interacting genes: APP ARHGEF10L CDKN2C DNAJB11 DR1 FBXO7 FEZ1 FEZ2 FOXH1 GTF2B LMO2 LNX1 LNX2 MCRS1 MORF4L1 NCK2 NFYB PICK1 PIK3R3 PLEKHF2 POLE3 RPL9 SDCBP SRPK2 TAF9 TAF9B TBP TK1 TNFRSF14 TTF2 ZEB1	18 interacting genes: BRD1 CLASP2 DRAP1 FEZ1 KPNA2 NEK1 PDCD7 PRKCZ RAB3GAP1 RAI14 SAP30L SCOC SMC3 TBC1D25 TEDC2 TLK2 WWC1 ZNF251
Entrez ID		10589	9637
HPRD ID		03796	09213
Ensembl ID		ENSG00000175550	ENSG00000171055
Uniprot IDs		Q14919	Q9UHY8
PDB IDs		1JFI
Enriched GO Terms of Interacting Partners?
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