FBLN5 and LGMN

		FBLN5	LGMN
Description		fibulin 5	legumain
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix Collagen-containing Extracellular Matrix Extracellular Exosome Elastic Fiber	Extracellular Region Cytoplasm Lysosome Late Endosome Endolysosome Lumen Lysosomal Lumen Apical Part Of Cell Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Integrin Binding Calcium Ion Binding Protein Binding Protein C-terminus Binding Extracellular Matrix Constituent Conferring Elasticity Protein Homodimerization Activity	Cysteine-type Endopeptidase Activity Peptidase Activity Tau Protein Binding
	Biological Process	Regulation Of Cell Growth Cell-matrix Adhesion Protein Localization To Cell Surface Secretion Elastic Fiber Assembly Regulation Of Removal Of Superoxide Radicals	Renal System Process Proteolysis Vacuolar Protein Processing Memory Positive Regulation Of Cell Population Proliferation Associative Learning Response To Acidic PH Negative Regulation Of Gene Expression Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Receptor Catabolic Process Cellular Response To Hepatocyte Growth Factor Stimulus Negative Regulation Of Multicellular Organism Growth Vitamin D Metabolic Process Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Mitotic Cell Cycle Proteolysis Involved In Cellular Protein Catabolic Process Cellular Response To Calcium Ion Positive Regulation Of Monocyte Chemotaxis Dendritic Spine Organization Activation Of Cysteine-type Endopeptidase Activity Self Proteolysis Positive Regulation Of Long-term Synaptic Potentiation Negative Regulation Of ERBB Signaling Pathway Cellular Response To Amyloid-beta Positive Regulation Of Endothelial Cell Chemotaxis
Pathways		Elastic fibre formation Molecules associated with elastic fibres Molecules associated with elastic fibres	Trafficking and processing of endosomal TLR Vitamin D (calciferol) metabolism MHC class II antigen presentation
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30578418) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Heel bone mineral density ( 30598549) Height ( 25429064 31562340 18391951) Hip circumference adjusted for BMI ( 34021172) Major depressive disorder ( 34099189) Major depressive disorder x sex interaction ( 34099189) Optic disc size ( 31809533) Pulse pressure ( 27841878 30578418) Waist circumference adjusted for body mass index ( 28552196)	Blood protein levels ( 30072576) Change in serum metabolite levels (CMS) ( 31636271) Systemic juvenile idiopathic arthritis ( 27927641)
Interacting Genes		23 interacting genes: ATN1 GFI1B GSC HOXA1 LGMN LOXL1 LPA MEOX2 NDUFA4 NUFIP2 OTX1 PAXIP1 PDIA3 PPP2R5C PRNP PSMC1 SERPINA1 SERPINA5 SOD3 ST3GAL3 TOP3B TRIP13 XCL1	6 interacting genes: FBLN5 LAMC3 MAPT SET SRPK2 USP17L2
Entrez ID		10516	5641
HPRD ID		05204	04017
Ensembl ID		ENSG00000140092	ENSG00000100600
Uniprot IDs		A0A024R6G3 Q9UBX5	Q53XC6 Q96CY7 Q99538
PDB IDs			4AW9 4AWA 4AWB 4FGU 4N6N 4N6O 5LU8 5LU9 5LUA 5LUB
Enriched GO Terms of Interacting Partners?
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