SHC1 and NTRK1

  • Number of citations of the paper that reports this interaction (PubMedID 8155326)
  • 131
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vivo, in vitro)

SHC1

NTRK1

Description SHC adaptor protein 1 neurotrophic receptor tyrosine kinase 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Red cell distribution width ( 32888494)
Interacting Genes 146 interacting genes: ALK AP2A1 AP2A2 APP AR AXL BCL3 BCR BUB1 C11orf58 CALCOCO2 CALD1 CBL CBLB CBLC CD22 CD247 CD3E CD81 CDH5 CEACAM1 CRK CRKL CSF1R CSF2RB CSF3R CSK DAG1 DDR1 DDR2 DNAH7 DOK1 DUSP23 EGFR EPHA2 EPOR EPS8 ERBB2 ERBB3 ERBB4 ESR1 FAM118B FBXW7 FCGR2A FCGR3A FGFR1 FGFR2 FLT1 FLT3 FLT4 FYN GAB1 GAB2 GEMIN7 GH1 GHR GRAP GRAP2 GRB2 GRB7 HMOX2 IGF1R IL2 IL2RB IL2RG IL4R IL6ST ILK INPP5D INPPL1 INSR IRS1 IRS2 ITGB3 ITGB4 JAK2 KDR KIT KRT18 LCK LCP2 LRP1 LTK LYN MAP4K1 MAPK1 MAPK14 MAPK6 MAPK8 MAPKAPK2 MET MME MPL MRPL44 MST1R NGFR NPM1 NTRK1 NTRK2 NTRK3 NUDT21 OSGEP PAG1 PAK1 PDGFRB PIK3C2B PIK3R1 PIK3R2 PLCG1 PLCG2 PLPP3 PLSCR1 PPP2R5A PRKCA PRKCD PRKRA PTK2 PTK2B PTPN11 PTPN12 PTPN2 PTPN6 RAPGEF1 RASA1 RB1 RET SH2B2 SHCBP1 SMAD4 SOS1 SOS2 SP1 SRC STAT5A STAT5B SUV39H2 SYK TEC TEK TH TPR TRIM15 UBASH3B VAV1 VAV3 ZAP70 41 interacting genes: ABL1 ARHGAP32 CAV1 CRK DNAJA3 DYNLL1 ERBB2 FRS2 FRS3 GIPC1 GRB2 HIPK2 IRS1 IRS2 KIDINS220 MAPK3 MATK NEDD4L NGF NGFR NTF3 PIK3R1 PLCG1 PTPN1 PTPN11 PTPRR RAP1A RASA1 RASGRF1 RUSC1 SH2B1 SH2B2 SHC1 SHC2 SHC3 SORT1 SQSTM1 TPTE TRAF4 TRAF6 UBB
Entrez ID 6464 4914
HPRD ID 02780 01869
Ensembl ID ENSG00000160691 ENSG00000198400
Uniprot IDs P29353 P04629 X5DR71
PDB IDs 1MIL 1N3H 1OY2 1QG1 1SHC 1TCE 1WCP 2L1C 4JMH 4XWX 5CZI 6DM4 1HE7 1SHC 1WWA 1WWW 2IFG 2N90 4AOJ 4CRP 4F0I 4GT5 4PMM 4PMP 4PMS 4PMT 4YNE 4YPS 5H3Q 5I8A 5JFS 5JFV 5JFW 5JFX 5KMI 5KMJ 5KMK 5KML 5KMM 5KMN 5KMO 5KVT 5WR7 6D1Y 6D1Z 6D20 6D22 6DKB 6DKG 6DKI 6DKW 6IQN 6J5L 6NPT 6NSP 6NSS 6PL1 6PL2 6PL3 6PL4 6PMA 6PMB 6PMC 6PME
Enriched GO Terms of Interacting Partners?
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