KATNB1 and DYNC1H1

Number of citations of the paper that reports this interaction (PubMedID 16203747)
54

Data Source:
BioGRID (pull down, affinity chromatography technology)

		KATNB1	DYNC1H1
Description		katanin regulatory subunit B1	dynein cytoplasmic 1 heavy chain 1
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Centrosome Spindle Cytosol Microtubule Plasma Membrane Katanin Complex Microtubule Cytoskeleton Membrane Growth Cone Midbody Neuronal Cell Body	Extracellular Region Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Cytoplasmic Microtubule Cell Cortex Membrane Filopodium Dynein Complex Azurophil Granule Lumen Extracellular Exosome Axon Cytoplasm
	Molecular Function	Protein Binding Microtubule Binding Protein Heterodimerization Activity ATPase Regulator Activity Dynein Complex Binding	RNA Binding Protein Binding ATP Binding Minus-end-directed Microtubule Motor Activity Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Protein Targeting Microtubule Depolymerization Negative Regulation Of Microtubule Depolymerization Mitotic Chromosome Movement Towards Spindle Pole Positive Regulation Of Cell Death Positive Regulation Of Neuron Projection Development Positive Regulation Of Microtubule Depolymerization Regulation Of Catalytic Activity Microtubule Severing Cell Division	Mitotic Cell Cycle Microtubule-based Movement Mitotic Spindle Organization Nuclear Migration Retrograde Axonal Transport Cytoplasmic Microtubule Organization Positive Regulation Of Intracellular Transport P-body Assembly Stress Granule Assembly Establishment Of Spindle Localization Cell Division Regulation Of Mitotic Spindle Organization Minus-end-directed Vesicle Transport Along Microtubule Regulation Of Metaphase Plate Congression Positive Regulation Of Cold-induced Thermogenesis Positive Regulation Of Spindle Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins Neutrophil degranulation COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase AURKA Activation by TPX2 HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
Interacting Genes		6 interacting genes: DYNC1H1 KATNA1 PAFAH1B1 RXFP3 TGFBR1 XRN1	29 interacting genes: ASB7 ATP2B3 BRCA1 COX20 DISC1 DUX4 DYNLL1 ECSIT EGFR KATNA1 KATNB1 LINC01554 LMO4 MRE11 MTNR1B NDEL1 PAFAH1B1 PPP2R5C PRKCD PSMB9 RHBDD2 SMAD2 SORBS2 SUMO2 TENT5A TNIK YWHAG YWHAQ ZBTB42
Entrez ID		10300	1778
HPRD ID		04081	02524
Ensembl ID		ENSG00000140854	ENSG00000197102
Uniprot IDs		Q9BVA0	Q14204
PDB IDs			2BOR 2BOT 5NUG 5OWO 6F1T 6F1U 6F1V 6F1Y 6F38 6F3A
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?