TRAIP and UBOX5

Number of citations of the paper that reports this interaction (PubMedID 22493164)
7

Data Source:
BioGRID (two hybrid)

		TRAIP	UBOX5
Description		TRAF interacting protein	U-box domain containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Perinuclear Region Of Cytoplasm Site Of DNA Damage	Nucleus Nucleoplasm Focal Adhesion Nuclear Body
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Ubiquitin Protein Ligase Binding Ubiquitin-ubiquitin Ligase Activity Metal Ion Binding
	Biological Process	Apoptotic Process Cellular Response To DNA Damage Stimulus Signal Transduction Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Protein Ubiquitination Replication Fork Processing Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interferon-beta Production Protein-DNA Covalent Cross-linking Repair	Protein Polyubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Blood protein levels ( 29875488 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) C-reactive protein levels ( 30388399) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) Fasting insulin ( 34059833) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mental health study participation (provided email address) ( 31263887) Multisite chronic pain ( 33830993) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Tea consumption ( 31046077) Walking pace ( 33128006)	Household income ( 31844048) Household income (MTAG) ( 31844048) Night sleep phenotypes ( 27126917)
Interacting Genes		28 interacting genes: ALOX15B APP CEP19 CYLD FLII LXN MAGEF1 MAPRE2 MAPRE3 POLK POLR1C RNF114 RNF4 TNFRSF1B TRAF1 TRAF2 TRIM23 TRIM41 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2H UBE2K UBE2U UBE2Z UBOX5 USP2	19 interacting genes: MLH1 NEDD4 TRAF6 TRAIP TRIM23 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2V1 UBE2W USP2 VCP
Entrez ID		10293	22888
HPRD ID		05811	15605
Ensembl ID		ENSG00000183763	ENSG00000185019
Uniprot IDs		Q9BWF2	O94941
PDB IDs		4ZTD
Enriched GO Terms of Interacting Partners?
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