SGK2 and IL3RA

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		SGK2	IL3RA
Description		serum/glucocorticoid regulated kinase 2	interleukin 3 receptor subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Receptor Complex
	Molecular Function	Protein Serine/threonine Kinase Activity ATP Binding Potassium Channel Regulator Activity Sodium Channel Regulator Activity Protein Serine Kinase Activity	Cytokine Receptor Activity Interleukin-3 Receptor Activity Protein Binding Cytokine Binding
	Biological Process	Regulation Of Cell Growth Protein Phosphorylation Response To Oxidative Stress Peptidyl-serine Phosphorylation Positive Regulation Of Transporter Activity Intracellular Signal Transduction Regulation Of Cell Population Proliferation	Cytokine-mediated Signaling Pathway Cellular Response To Interleukin-3 Interleukin-3-mediated Signaling Pathway
Pathways		Stimuli-sensing channels	Interleukin-3, Interleukin-5 and GM-CSF signaling RAF/MAP kinase cascade Interleukin receptor SHC signaling
Drugs			Sargramostim Tagraxofusp
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Weight ( 34074324)	Schizophrenia ( 17522711)
Interacting Genes		9 interacting genes: APP DAPK1 HIRIP3 IL3RA NEDD4 NEDD4L PDPK1 PMM2 SAP130	32 interacting genes: BMP10 C2CD2L CDC25A CDK1 CISH CLDN19 CSF2 CSF2RB EMP3 FOXP1 GIMAP1 GNA12 IL3 JAGN1 JAK1 JAK2 LNX1 NINJ2 NR0B2 PAQR5 PPP1CC SAE1 SERP1 SGK2 SMAGP SYS1 TMEM128 TMEM147 TMEM254 TMEM65 TRARG1 VAMP5
Entrez ID		10110	3563
HPRD ID		06348	02392
Ensembl ID		ENSG00000101049	ENSG00000185291
Uniprot IDs		Q9HBY8	P26951
PDB IDs			4JZJ 5UV8 5UWC 6NMY
Enriched GO Terms of Interacting Partners?
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