ARPC1B and ARPC5

Number of citations of the paper that reports this interaction (PubMedID 11721045)
189

Data Source:
HPRD (in vitro)

		ARPC1B	ARPC5
Description		actin related protein 2/3 complex subunit 1B	actin related protein 2/3 complex subunit 5
Image
GO Annotations	Cellular Component	Nucleus Cytosol Arp2/3 Protein Complex Focal Adhesion Actin Cytoskeleton Tubulobulbar Complex Extracellular Exosome	Extracellular Region Nucleus Cytoplasm Endosome Cytosol Arp2/3 Protein Complex Focal Adhesion Actin Cytoskeleton Lamellipodium Growth Cone Secretory Granule Lumen Site Of Double-strand Break Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Actin Filament Binding	Structural Constituent Of Cytoskeleton Protein Binding Actin Filament Binding
	Biological Process	Response To Estradiol Arp2/3 Complex-mediated Actin Nucleation Response To Estrogen	Smooth Muscle Cell Migration Cell Migration Orbitofrontal Cortex Development Maintenance Of Cell Polarity Actin Cytoskeleton Organization Arp2/3 Complex-mediated Actin Nucleation Actin Filament Network Formation Microtubule Organizing Center Localization Lamellipodium Organization
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Neutrophil degranulation Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs		N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one	N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS		Alcohol consumption ( 31358974) Facial emotion recognition (sad faces) ( 28608620) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Serum metabolite levels ( 23093944)
Interacting Genes		12 interacting genes: ACTB ACTR2 APP ARPC2 ARPC4 ARPC5 AURKA KEAP1 PAK1 PMPCB SRPK2 WAS	6 interacting genes: ACTR2 ACTR3 ARPC1B ARPC4 MAPKAPK2 NR3C1
Entrez ID		10095	10092
HPRD ID		10366	11969
Ensembl ID		ENSG00000130429	ENSG00000162704
Uniprot IDs		A4D275 O15143	O15511
PDB IDs		6UHC 6YW6	6UHC 6YW7
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?