ARPC5 and ACTR2

Number of citations of the paper that reports this interaction (PubMedID 11721045)
189

Data Source:
HPRD (in vitro)

		ARPC5	ACTR2
Description		actin related protein 2/3 complex subunit 5	actin related protein 2
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Endosome Cytosol Arp2/3 Protein Complex Focal Adhesion Actin Cytoskeleton Lamellipodium Growth Cone Secretory Granule Lumen Site Of Double-strand Break Extracellular Exosome Ficolin-1-rich Granule Lumen	Extracellular Region Nucleus Cytoplasm Cytosol Arp2/3 Protein Complex Focal Adhesion Postsynaptic Density Actin Cytoskeleton Membrane Lamellipodium Actin Cap Azurophil Granule Lumen Site Of Double-strand Break Podosome Core Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Actin Filament Binding	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Actin Filament Binding
	Biological Process	Smooth Muscle Cell Migration Cell Migration Orbitofrontal Cortex Development Maintenance Of Cell Polarity Actin Cytoskeleton Organization Arp2/3 Complex-mediated Actin Nucleation Actin Filament Network Formation Microtubule Organizing Center Localization Lamellipodium Organization	Establishment Or Maintenance Of Cell Polarity Associative Learning Asymmetric Cell Division Positive Regulation Of Lamellipodium Assembly Meiotic Chromosome Movement Towards Spindle Pole Cytosolic Transport Meiotic Cytokinesis Arp2/3 Complex-mediated Actin Nucleation Response To Immobilization Stress Cellular Response To Trichostatin A Response To Ethanol Positive Regulation Of Transcription By RNA Polymerase II Spindle Localization Cilium Assembly Positive Regulation Of Dendritic Spine Morphogenesis Cellular Response To Interferon-gamma Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Neutrophil degranulation Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Neutrophil degranulation Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs		N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one	N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS			Calcific aortic valve stenosis ( 32141789) Coronary artery disease ( 29212778 33020668) Heel bone mineral density ( 30598549) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Metabolite levels ( 23823483)
Interacting Genes		6 interacting genes: ACTR2 ACTR3 ARPC1B ARPC4 MAPKAPK2 NR3C1	15 interacting genes: ACTC1 ACTR3 ARPC1B ARPC4 ARPC5 BMP2 ELF5 ERCC6 FCGR2A HCLS1 IQGAP2 SHARPIN WASF1 WASF2 WASL
Entrez ID		10092	10097
HPRD ID		11969	05023
Ensembl ID		ENSG00000162704	ENSG00000138071
Uniprot IDs		O15511	P61160
PDB IDs		6UHC 6YW7	6UHC 6YW6 6YW7
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?