KCNK7 and CFHR5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KCNK7	CFHR5
Description		potassium two pore domain channel subfamily K member 7	complement factor H related 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Region Protein-containing Complex
	Molecular Function	Voltage-gated Ion Channel Activity Potassium Channel Activity Potassium Ion Leak Channel Activity	Protein Binding Identical Protein Binding Protein Heterodimerization Activity
	Biological Process	Potassium Ion Transport Stabilization Of Membrane Potential Regulation Of Ion Transmembrane Transport Potassium Ion Transmembrane Transport	Complement Activation, Alternative Pathway Negative Regulation Of Protein Binding Cytolysis By Host Of Symbiont Cells
Pathways		Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) Phase 4 - resting membrane potential	Regulation of Complement cascade
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Rosacea symptom severity ( 29771307)	Age-related macular degeneration ( 23577725 23536807) Age-related macular degeneration (extreme sampling) ( 23577725) Age-related macular degeneration (MTAG) ( 32277175) Asthma ( 29273806) Blood protein levels ( 29875488 28240269) Lupus nephritis in systemic lupus erythematosus ( 24925725) Matrix metalloproteinase-8 levels ( 29212897) Nephropathy ( 21399633)
Interacting Genes		1 interacting genes: CFHR5	20 interacting genes: ARL13B C3 CISD2 CREB3 CREB3L1 EBAG9 ERGIC3 FFAR2 GPX8 KCNK7 LMNA MFSD14B PANX1 SLC10A1 SLC18A2 SLC4A1 STOM TMEM14B TMEM237 TMPRSS2
Entrez ID		10089	81494
HPRD ID		06804	06508
Ensembl ID		ENSG00000173338	ENSG00000134389
Uniprot IDs		A0A024R5B0 A0A024R5F5 Q3SYI1 Q9Y2U2	Q9BXR6
PDB IDs
Enriched GO Terms of Interacting Partners?
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