PQBP1 and SFTPC

Number of citations of the paper that reports this interaction (PubMedID 19366705)
10

Data Source:
BioGRID (pull down)

		PQBP1	SFTPC
Description		polyglutamine binding protein 1	surfactant protein C
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytoplasmic Stress Granule Nuclear Body Nuclear Speck Neuronal Ribonucleoprotein Granule	Extracellular Region Extracellular Space Endoplasmic Reticulum Membrane Lamellar Body Clathrin-coated Endocytic Vesicle Alveolar Lamellar Body Multivesicular Body Lumen
	Molecular Function	DNA Binding Double-stranded DNA Binding Transcription Coactivator Activity Protein Binding Ribonucleoprotein Complex Binding	Protein Binding Identical Protein Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response Positive Regulation Of Defense Response To Virus By Host Regulation Of Transcription, DNA-templated Neuron Projection Development Positive Regulation Of Type I Interferon Production Regulation Of RNA Splicing Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Dendrite Morphogenesis Defense Response To Virus Cellular Response To Exogenous DsRNA	Respiratory Gaseous Exchange By Respiratory System
Pathways		mRNA Splicing - Major Pathway	Surfactant metabolism Defective pro-SFTPC causes SMDP2 and RDS Defective CSF2RB causes SMDP5 Defective CSF2RA causes SMDP4
Drugs
Diseases
GWAS			Coronary artery disease ( 29212778) Hypertriglyceridemia ( 23505323)
Interacting Genes		24 interacting genes: APBB1 APP AQR ATXN1 CLTB EEF1A1 ERG28 ESR1 GOLGA2 HNRNPH2 LNX1 LRIF1 LZTS2 MAPRE1 MED31 POLR2A POU3F2 RAB8A RCVRN SFTPC TLX3 TXNL4A WBP11 WDR77	36 interacting genes: BSCL2 CD200R1 CD79A CLDN5 CPLX4 CREB3 CXCL9 FAM209A FNDC9 GJA8 GOLM1 GPR152 GPX8 HPN ICAM3 IFNGR2 KLRC1 LMNA LSMEM2 MUC1 NEDD4 PDZK1IP1 PQBP1 PVR SEC22A SEC61G SIGLEC9 SMIM3 SYNE4 TMEM106C TMEM139 TMEM30B TMEM79 TMPRSS2 WWP1 WWP2
Entrez ID		10084	6440
HPRD ID		02354	01520
Ensembl ID		ENSG00000102103	ENSG00000168484
Uniprot IDs		A0A0S2Z4V5 O60828	A0A0A0MTC9 A0A0S2Z4Q0 E5RI64 P11686
PDB IDs		4BWQ 4BWS 4CDO	2YAD
Enriched GO Terms of Interacting Partners?
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