STRBP and MIR199A1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		STRBP	MIR199A1
Description		spermatid perinuclear RNA binding protein	microRNA 199a-1
Image			No pdb structure
GO Annotations	Cellular Component	Manchette Nucleus Cytoplasm	Extracellular Space
	Molecular Function	DNA Binding RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding Microtubule Binding	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Spermatid Development Mechanosensory Behavior	Re-entry Into Mitotic Cell Cycle Negative Regulation Of Receptor Internalization Positive Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Autophagy Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Gene Expression Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of TOR Signaling Negative Regulation Of Hepatocyte Growth Factor Production Gene Silencing By MiRNA Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Myoblast Differentiation Regulation Of Angiogenesis Positive Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Positive Regulation Of Protein Kinase B Signaling Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Lung Blood Pressure Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Metallopeptidase Activity Positive Regulation Of Cardiac Muscle Tissue Regeneration Regulation Of Connective Tissue Replacement Positive Regulation Of Connective Tissue Replacement Positive Regulation Of Myoblast Proliferation
Pathways
Drugs
Diseases
GWAS		Birth weight ( 27680694) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Height ( 31562340 31217584) Lymphocyte counts ( 32888494)
Interacting Genes		59 interacting genes: ADARB1 ARNT CAMK2G DAB1 EIF2AK2 HMGXB4 LRRK2 MAP4 MIR1-1 MIR1-2 MIR106A MIR122 MIR128-2 MIR138-1 MIR141 MIR143 MIR145 MIR155 MIR15B MIR16-2 MIR199A1 MIR199A2 MIR19A MIR200A MIR200B MIR200C MIR214 MIR221 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR429 MIR7-1 MIR7-3 MIR9-1 MIR9-3 MIR92A1 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7C MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G PRKRA RBFOX1 RBPMS RBPMS2 STAU1 THAP1 ZMAT4 ZNF346	83 interacting genes: AIMP1 AIMP2 C1QBP CELF1 CELF2 CPSF1 CPSF6 CPSF7 DARS1 DDX1 DDX21 DDX3X DDX49 DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FUS HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SAFB SF3A3 SF3B1 SF3B2 SF3B3 SFPQ SPOUT1 STRBP SYMPK SYNCRIP TAF15 TIAL1 TRA2A TRA2B UPF1 UTP20 YBX1 YBX2 YBX3
Entrez ID		55342	406976
HPRD ID		10257
Ensembl ID		ENSG00000165209	ENSG00000207752
Uniprot IDs		A0A0S2Z5K8 Q96SI9 V9HWK4
PDB IDs		2DMY
Enriched GO Terms of Interacting Partners?
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