TOM1L1 and PELP1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TOM1L1	PELP1
Description		target of myb1 like 1 membrane trafficking protein	proline, glutamate and leucine rich protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Golgi Stack Cytosol Endosome Membrane Membrane Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Transcriptionally Active Chromatin MLL1 Complex
	Molecular Function	Protein Binding SH3 Domain Binding Protein Kinase Binding Clathrin Binding Protein Kinase Activator Activity Phosphatidylinositol Binding Ubiquitin Binding	Chromatin Binding RNA Binding Protein Binding Transcription Factor Binding SUMO Binding Protein N-terminus Binding ATPase Binding
	Biological Process	Signal Transduction Protein Transport Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Mitotic Nuclear Division Regulation Of DNA Biosynthetic Process	Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Estrogen Stimulus
Pathways			Major pathway of rRNA processing in the nucleolus and cytosol PTK6 Expression
Drugs
Diseases
GWAS		Carotid intima media thickness x smoking interaction ( 32117412) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965) Systolic blood pressure ( 34074324) Urinary albumin-to-creatinine ratio ( 32600054)	Eosinophil counts ( 29403010)
Interacting Genes		29 interacting genes: AMFR CCDC47 CELF1 COPS7A CWF19L1 DNAJB13 FYN GLUD2 GRB2 GSN HGS HNRNPH1 MAP3K3 NDC80 NOMO1 PDPN PELP1 PHYH PIK3R1 PWP2 RAB18 TASOR TOLLIP TSG101 TUBA1B UBC UBXN4 VAV2 VCP	25 interacting genes: AR BAG6 BCAS3 BLOC1S1 CREBBP EP300 ESR1 ESR2 H1-1 H2AC20 H2BC21 H3-3A H4C1 HGS NFKB1 NR3C1 PTEN RB1 SMAD9 SNCA SRC STAT3 SUMO2 TOM1L1 TP53
Entrez ID		10040	27043
HPRD ID		05266	10144
Ensembl ID		ENSG00000141198	ENSG00000141456
Uniprot IDs		O75674 Q8NI65	B4DEX7 B4DR36 C9JFV4 E7EV54 Q8IZL8
PDB IDs		3RRU
Enriched GO Terms of Interacting Partners?
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