PAPPA

Description		pappalysin 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Metalloendopeptidase Activity Protein Binding Metallopeptidase Activity Zinc Ion Binding
	Biological Process	Proteolysis Female Pregnancy Response To Follicle-stimulating Hormone Cellular Protein Metabolic Process Response To Glucocorticoid
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Birth weight ( 31043758) Brain morphology (MOSTest) ( 32665545) Conotruncal heart defects ( 24800985) Haemorrhoidal disease ( 33888516) Heel bone mineral density ( 28869591) Height ( 28552196 20881960 18391950) Hip circumference adjusted for BMI ( 34021172) Intralaminar thalamic nuclei volume ( 34006833) Metabolite levels ( 23823483) Pulse pressure ( 30224653) Symptoms in placebo-treated COVID-19 outpatients at risk of severe disease (time to remission) ( 34035401)
Interacting Genes		11 interacting genes: ATF7IP C3 CREBBP IGFBP4 PLG PRG2 SKIL SMAD2 SMAD3 SMAD9 TNNI3
Entrez ID		5069
HPRD ID		01448
Ensembl ID		ENSG00000182752
Uniprot IDs		B4DTA8 Q13219 Q7Z613
PDB IDs
Enriched GO Terms of Interacting Partners?
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