PIK3R4

Description		phosphoinositide-3-kinase regulatory subunit 4
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GO Annotations	Cellular Component	Late Endosome Autophagosome Cytosol Axoneme Microtubule Cytoskeleton Membrane Phagocytic Vesicle Membrane Phosphatidylinositol 3-kinase Complex, Class III, Type I Phosphatidylinositol 3-kinase Complex, Class III, Type II Phosphatidylinositol 3-kinase Complex, Class III Intracellular Membrane-bounded Organelle Nucleus-vacuole Junction
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Protein Phosphorylation Protein Targeting To Vacuole Macroautophagy Autophagy Of Peroxisome Regulation Of Cytokinesis Receptor Catabolic Process Cellular Response To Glucose Starvation Positive Regulation Of Phosphatidylinositol 3-kinase Activity Late Endosome To Vacuole Transport
Pathways		PI3K Cascade Macroautophagy Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the late endosome membrane Toll Like Receptor 9 (TLR9) Cascade RHO GTPases Activate NADPH Oxidases Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Abdominal aortic calcification levels ( 31659325) Refractive error ( 32231278)
Interacting Genes		8 interacting genes: FNDC3B MAPRE1 NPHP3 NRBF2 PIK3C3 RACK1 SMAD6 YWHAB
Entrez ID		30849
HPRD ID		04010
Ensembl ID		ENSG00000196455
Uniprot IDs		Q99570
PDB IDs		7BL1
Enriched GO Terms of Interacting Partners?
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