DTX1

Description		deltex E3 ubiquitin ligase 1
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Nuclear Body
	Molecular Function	Transcription Coactivator Activity Notch Binding Protein Binding Zinc Ion Binding SH3 Domain Binding Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity
	Biological Process	Transcription, DNA-templated Transcription By RNA Polymerase II Cell Surface Receptor Signaling Pathway Notch Signaling Pathway Regulation Of Notch Signaling Pathway Glial Cell Differentiation Protein Ubiquitination Negative Regulation Of T Cell Differentiation Negative Regulation Of Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Cellular Response To Leukemia Inhibitory Factor
Pathways		Activated NOTCH1 Transmits Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus
Drugs
Diseases
GWAS		Body mass index ( 26426971) Coffee consumption ( 29367735) Retinitis pigmentosa ( 33514863) Visceral adipose tissue adjusted for BMI ( 22589738) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		21 interacting genes: DEFA5 DTX2 DTX3 DTX3L EP300 G3BP1 GRB2 ITCH MAP3K1 NOTCH1 NOTCH2 PRKAR1A TAX1BP3 UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2N UBE2U
Entrez ID		1840
HPRD ID		03991
Ensembl ID		ENSG00000135144
Uniprot IDs		Q86Y01
PDB IDs		6Y5N 6Y5P
Enriched GO Terms of Interacting Partners?
Tagcloud ?