SLC12A6 and OXSR1

Number of citations of the paper that reports this interaction (PubMedID 12386165)
138

Data Source:
HPRD (two hybrid)

		SLC12A6	OXSR1
Description		solute carrier family 12 member 6	oxidative stress responsive kinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Synapse	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Potassium:chloride Symporter Activity	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Identical Protein Binding
	Biological Process	Angiogenesis Ion Transport Cell Volume Homeostasis Chemical Synaptic Transmission Chloride Ion Homeostasis Potassium Ion Homeostasis Cellular Hypotonic Salinity Response Chloride Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Protein Phosphorylation Response To Oxidative Stress Osmosensory Signaling Pathway Regulation Of Mitotic Cell Cycle Positive Regulation Of T Cell Chemotaxis Peptidyl-threonine Phosphorylation Signal Transduction By Protein Phosphorylation Signal Transduction By Trans-phosphorylation Stress-activated Protein Kinase Signaling Cascade Activation Of Protein Kinase Activity Intracellular Signal Transduction Chemokine (C-C Motif) Ligand 21 Signaling Pathway Chemokine (C-X-C Motif) Ligand 12 Signaling Pathway Protein Autophosphorylation Cellular Hypotonic Response Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Cellular Response To Chemokine
Pathways		Cation-coupled Chloride cotransporters Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)
Drugs		Potassium Chloride
Diseases		Agenesis of the corpus callosum with peripheral neuropathy (ACCPN)
GWAS		Barrett's esophagus x pack-years of smoking exposure interaction ( 29551738)	Gut microbiota (bacterial taxa) ( 27723756) Mean corpuscular hemoglobin concentration ( 29403010)
Interacting Genes		2 interacting genes: OXSR1 STK39	10 interacting genes: APP BMPR1B GORASP1 PAK1 RELL1 SLC12A1 SLC12A2 SLC12A6 SMURF1 TGFBR1
Entrez ID		9990	9943
HPRD ID		09220	06809
Ensembl ID		ENSG00000140199	ENSG00000172939
Uniprot IDs		A0A024R9I5 A0A024R9K8 Q6NSI7 Q9UHW9	O95747
PDB IDs			2V3S 2VWI 3DAK
Enriched GO Terms of Interacting Partners?
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