NR1I3 and IGH

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		NR1I3	IGH
Description		nuclear receptor subfamily 1 group I member 3	immunoglobulin heavy locus
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton RNA Polymerase II Transcription Factor Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Steroid Hormone Receptor Activity Transcription Coactivator Activity Nuclear Receptor Activity Transcription Factor Binding Zinc Ion Binding Nuclear Receptor Transcription Coactivator Activity Signaling Receptor Activity Transcription Factor Activity, Direct Ligand Regulated Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Lipid Metabolic Process Signal Transduction Multicellular Organism Development Cell Differentiation Intracellular Receptor Signaling Pathway Response To Lipid Cholesterol Homeostasis Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Lipid Homeostasis Cellular Response To Lipopolysaccharide
Pathways
Drugs		Clotrimazole Doxylamine Meclizine Loperamide Ketoconazole Pheniramine Prasterone 16,17-Androstene-3-Ol Resveratrol Cholesterol Phenolphthalein (5BETA)-PREGNANE-3,20-DIONE Hexestrol Triclosan
Diseases
GWAS		Blood metabolite levels ( 24816252)	Alzheimer's disease (late onset) ( 24162737) Baseline cortisol levels in response to low dose short synacthen test in corticosteroid treated asthma ( 29551627) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG monosialylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392)
Interacting Genes		18 interacting genes: CHD9 DNMT3L FTH1 HNF4A IGH MAP4 MED1 NCOA1 NCOA3 NR0B2 POU1F1 PPARGC1A PSMC4 PSMC5 RXRA SNRPD3 SNX13 SRC	2 interacting genes: FBXO2 NR1I3
Entrez ID		9970	3492
HPRD ID		04858
Ensembl ID		ENSG00000143257
Uniprot IDs		F1DAL4 Q14994
PDB IDs		1XV9 1XVP
Enriched GO Terms of Interacting Partners?
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