MED13 and TSC22D2

Number of citations of the paper that reports this interaction (PubMedID 27337956)
18

Data Source:
BioGRID (two hybrid)

		MED13	TSC22D2
Description		mediator complex subunit 13	TSC22 domain family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Membrane Mediator Complex
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Nuclear Receptor Transcription Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Cholesterol Homeostasis Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Triglyceride Homeostasis	Regulation Of Transcription By RNA Polymerase II Response To Osmotic Stress
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Coffee consumption ( 31046077) Initial pursuit acceleration ( 29064472) Objective response to lithium treatment ( 26503763) PR segment ( 24850809)	Adiponectin levels ( 22479202) Cognitive decline rate in late mild cognitive impairment ( 26252872) Glaucoma ( 31959993) Glaucoma (primary open-angle) ( 29891935) Intraocular pressure ( 29235454) Macular thickness ( 30535121) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Moyamoya disease ( 29273593) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149) Type 2 diabetes ( 30054458 30297969) Waist circumference ( 26785701)
Interacting Genes		8 interacting genes: ESR1 MED12 MED13L MED23 MED29 MED9 SREBF1 TSC22D2	43 interacting genes: ANAPC10 ANKRD36 ARID2 ATP1B1 CCDC141 CCDC144A CLIP1 ENOPH1 EPCAM F8 FLNB GPBP1 ITGA2 KIAA0586 LOXHD1 LPL LRRC6 MED13 MPDZ MSH3 MTIF2 NGRN NRBP1 OSBPL1A PRMT3 PSMA7 PSMA8 RBL1 REV1 RNF2 SAP18 SCEL SEC31A SNX3 SPEF2 STK39 TMA7 TTN UFM1 WNK3 ZMYM2 ZNF143 ZNF251
Entrez ID		9969	9819
HPRD ID		07229	11101
Ensembl ID		ENSG00000108510	ENSG00000196428
Uniprot IDs		A0A024QZ75 Q9UHV7	B4DN36 O75157
PDB IDs
Enriched GO Terms of Interacting Partners?
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