MED13 and MED13L

Number of citations of the paper that reports this interaction (PubMedID 15175163)
116

Data Source:
HPRD (in vivo)

		MED13	MED13L
Description		mediator complex subunit 13	mediator complex subunit 13L
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Membrane Mediator Complex	Mediator Complex
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Nuclear Receptor Transcription Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding	Transcription Coregulator Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Cholesterol Homeostasis Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Triglyceride Homeostasis	Regulation Of Transcription By RNA Polymerase II
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases			Transposition of great arteries
GWAS		Coffee consumption ( 31046077) Initial pursuit acceleration ( 29064472) Objective response to lithium treatment ( 26503763) PR segment ( 24850809)	Blond vs. brown/black hair color ( 30531825) Chronic obstructive pulmonary disease ( 30804561) Cognitive decline rate in late mild cognitive impairment ( 26252872) Colorectal cancer ( 21761138) Colorectal cancer or advanced adenoma ( 30510241) Corneal astigmatism ( 30306274) Diabetic kidney disease ( 26305897) Diastolic blood pressure ( 29403010 25249183) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Heart rate response to recovery post exercise ( 29769521) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Heel bone mineral density ( 30598549) Height ( 28552196 31562340) Hippocampal volume ( 29274321) Hypertension ( 25249183) Left ventricular QRS voltage ( 27195777) Lung function (FEV1) ( 26635082) Lung function (FVC) ( 28166213 26635082) Mean arterial pressure ( 29403010) Nose morphology ( 29921221) PR interval ( 30046033) Pulse pressure ( 30224653) Systolic blood pressure ( 29403010 25249183) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Total body bone mineral density ( 29304378) Urate levels in overweight individuals ( 25811787)
Interacting Genes		8 interacting genes: ESR1 MED12 MED13L MED23 MED29 MED9 SREBF1 TSC22D2	1 interacting genes: MED13
Entrez ID		9969	23389
HPRD ID		07229	10579
Ensembl ID		ENSG00000108510	ENSG00000123066
Uniprot IDs		A0A024QZ75 Q9UHV7	A0A3B3IRX3 Q71F56
PDB IDs
Enriched GO Terms of Interacting Partners?
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