MVP and MT-CYB

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		MVP	MT-CYB
Description		major vault protein	cytochrome b
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Nuclear Pore Cytoplasm Cytosol Cytoskeleton Membrane Secretory Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Lumen	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Intrinsic Component Of Membrane Integral Component Of Mitochondrial Inner Membrane
	Molecular Function	Protein Binding Protein Kinase Binding Protein Phosphatase Binding Identical Protein Binding	Ubiquinol-cytochrome-c Reductase Activity Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Protein Transport Regulation Of Signaling Negative Regulation Of Signaling Negative Regulation Of Protein Autophosphorylation ERBB Signaling Pathway Neutrophil Degranulation MRNA Transport Negative Regulation Of Protein Tyrosine Kinase Activity	Response To Hypoxia Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Response To Heat Electron Transport Coupled Proton Transport Animal Organ Regeneration Response To Cobalamin Response To Glucagon Hyperosmotic Salinity Response Response To Ethanol Response To Cadmium Ion Response To Copper Ion Response To Mercury Ion Response To Calcium Ion Response To Hyperoxia
Pathways		Neutrophil degranulation	Respiratory electron transport
Drugs			2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE 5-HEPTYL-6-HYDROXY-1,3-BENZOTHIAZOLE-4,7-DIONE (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE FAMOXADONE METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE UBIQUINONE-2
Diseases			Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS
Interacting Genes		58 interacting genes: ADAMTSL4 BANP C1orf94 CALCOCO2 CAMK2B CKAP4 DISC1 DLX2 EPHX2 ESR1 GIT2 GOLGA2 HP IHO1 KCTD9 KPNA2 KPNA3 MDFI MEOX1 MEOX2 MID2 MRTFA MT-CYB NNT NOTCH2NLA PARP4 PIH1D2 PLSCR1 POT1 PSTPIP1 PTEN PTPN11 RAB3IP RBPMS REL RHOXF2 RIMBP3 RNF111 SAXO1 SERTAD1 SKIL SLC2A4 STN1 TCF4 TENT5C TFCP2 TLE5 TP53 TRAF2 TRIM27 TRIM42 TRIP13 TRIP6 TSPOAP1 UBC VAC14 ZBTB32 ZMIZ2	2 interacting genes: KRAS MVP
Entrez ID		9961	4519
HPRD ID		05475	02468
Ensembl ID		ENSG00000013364	ENSG00000198727
Uniprot IDs		Q14764 X5D2M8 X5D7K9 X5DNU0	P00156 Q0ZFD6
PDB IDs		1Y7X	5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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