WASHC5 and WASHC1

Number of citations of the paper that reports this interaction (PubMedID 22939629)
262

Data Source:
BioGRID (affinity chromatography technology, two hybrid, biochemical)

		WASHC5	WASHC1
Description		WASH complex subunit 5	WASH complex subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Early Endosome Endoplasmic Reticulum Cytosol Neuron Projection Neuronal Cell Body WASH Complex	Exocyst Early Endosome Late Endosome Autophagosome Centriole Cytosol Early Endosome Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Recycling Endosome Membrane WASH Complex Invadopodium
	Molecular Function	Protein Binding	Actin Binding Protein Binding Ubiquitin Protein Ligase Binding Alpha-tubulin Binding
	Biological Process	Oocyte Maturation Positive Regulation Of Neuron Projection Development Protein Transport Endosomal Transport Cellular Protein-containing Complex Localization Polar Body Extrusion After Meiotic Divisions Regulation Of Actin Nucleation Spindle Assembly Involved In Meiosis Regulation Of Vesicle Size	Exocytosis Negative Regulation Of Autophagy Protein Transport Endosomal Transport Extracellular Matrix Disassembly Positive Regulation Of Cell Migration Positive Regulation Of Pseudopodium Assembly Regulation Of Protein Ubiquitination Arp2/3 Complex-mediated Actin Nucleation Retrograde Transport, Endosome To Golgi Negative Regulation Of Phosphatidylinositol 3-kinase Activity Retrograde Transport, Endosome To Plasma Membrane
Pathways
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS
Interacting Genes		2 interacting genes: WASHC1 WASHC2C	5 interacting genes: BECN1 BLOC1S2 RNF2 WASHC4 WASHC5
Entrez ID		9897	100287171
HPRD ID		13786
Ensembl ID		ENSG00000164961	ENSG00000181404
Uniprot IDs		E7EQI7 Q12768	A8K0Z3
PDB IDs
Enriched GO Terms of Interacting Partners?
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