WASHC1 and WASHC5

Number of citations of the paper that reports this interaction (PubMedID 22939629)
262

Data Source:
BioGRID (affinity chromatography technology, two hybrid, biochemical)

		WASHC1	WASHC5
Description		WASH complex subunit 1	WASH complex subunit 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Exocyst Early Endosome Late Endosome Autophagosome Centriole Cytosol Early Endosome Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Recycling Endosome Membrane WASH Complex Invadopodium	Nucleoplasm Early Endosome Endoplasmic Reticulum Cytosol Neuron Projection Neuronal Cell Body WASH Complex
	Molecular Function	Actin Binding Protein Binding Ubiquitin Protein Ligase Binding Alpha-tubulin Binding	Protein Binding
	Biological Process	Exocytosis Negative Regulation Of Autophagy Protein Transport Endosomal Transport Extracellular Matrix Disassembly Positive Regulation Of Cell Migration Positive Regulation Of Pseudopodium Assembly Regulation Of Protein Ubiquitination Arp2/3 Complex-mediated Actin Nucleation Retrograde Transport, Endosome To Golgi Negative Regulation Of Phosphatidylinositol 3-kinase Activity Retrograde Transport, Endosome To Plasma Membrane	Oocyte Maturation Positive Regulation Of Neuron Projection Development Protein Transport Endosomal Transport Cellular Protein-containing Complex Localization Polar Body Extrusion After Meiotic Divisions Regulation Of Actin Nucleation Spindle Assembly Involved In Meiosis Regulation Of Vesicle Size
Pathways
Drugs
Diseases			Hereditary spastic paraplegia (SPG)
GWAS
Interacting Genes		5 interacting genes: BECN1 BLOC1S2 RNF2 WASHC4 WASHC5	2 interacting genes: WASHC1 WASHC2C
Entrez ID		100287171	9897
HPRD ID			13786
Ensembl ID		ENSG00000181404	ENSG00000164961
Uniprot IDs		A8K0Z3	E7EQI7 Q12768
PDB IDs
Enriched GO Terms of Interacting Partners?
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