FCHSD2 and CHKA

Number of citations of the paper that reports this interaction (PubMedID 18654987)
16

Data Source:
BioGRID (two hybrid)

		FCHSD2	CHKA
Description		FCH and double SH3 domains 2	choline kinase alpha
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GO Annotations	Cellular Component	Plasma Membrane Clathrin-coated Pit Cell Junction Neuromuscular Junction Recycling Endosome Stereocilium Shaft	Cytosol
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding	Choline Kinase Activity Cholinesterase Activity Ethanolamine Kinase Activity ATP Binding Drug Binding Choline Binding Identical Protein Binding
	Biological Process	Neuromuscular Synaptic Transmission Protein Transport Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Multi-organism Membrane Organization Clathrin-dependent Endocytosis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Ethanolamine Metabolic Process Lipid Metabolic Process Phosphatidylethanolamine Biosynthetic Process Phosphatidylcholine Biosynthetic Process CDP-choline Pathway Lipid Transport Response To Toxic Substance Phosphorylation Choline Metabolic Process Response To 3-methylcholanthrene
Pathways			Synthesis of PC Synthesis of PE
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Crohn's disease ( 23850713 23266558) Endometrial cancer (endometrioid histology) ( 30093612) Health literacy ( 31250787) Serum total protein level ( 29403010) Systemic lupus erythematosus ( 26663301)
Interacting Genes		26 interacting genes: ABCF3 C2orf73 C9orf78 CASK CCDC158 CCDC85B CCT2 CFAP36 CHKA DAPP1 FAM9B HGS HSP90AB1 HSPA5 HTRA1 ITSN1 ITSN2 KIFC3 MSL1 MTUS2 PDE4DIP SH3BGR SRP72 VCPIP1 WAS WASL	6 interacting genes: APP DEPTOR FCHSD2 PSEN2 RCC1 SKP2
Entrez ID		9873	1119
HPRD ID		13321	00327
Ensembl ID		ENSG00000137478	ENSG00000110721
Uniprot IDs		O94868	P35790
PDB IDs		2DL5 2DL7 6GBU	2CKO 2CKP 2CKQ 2I7Q 3F2R 3G15 3ZM9 4BR3 4CG8 4CG9 4CGA 4DA5 5AFV 5EQE 5EQP 5EQY 5FTG 5FUT 5W6O
Enriched GO Terms of Interacting Partners?
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