FCHSD2 and CCT2

Number of citations of the paper that reports this interaction (PubMedID 18654987)
16

Data Source:
BioGRID (two hybrid)

		FCHSD2	CCT2
Description		FCH and double SH3 domains 2	chaperonin containing TCP1 subunit 2
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GO Annotations	Cellular Component	Plasma Membrane Clathrin-coated Pit Cell Junction Neuromuscular Junction Recycling Endosome Stereocilium Shaft	Zona Pellucida Receptor Complex Extracellular Region Cytosol Chaperonin-containing T-complex Microtubule Azurophil Granule Lumen Cell Body Extracellular Exosome
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding	Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Protein Binding Involved In Protein Folding Unfolded Protein Binding
	Biological Process	Neuromuscular Synaptic Transmission Protein Transport Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Multi-organism Membrane Organization Clathrin-dependent Endocytosis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Protein Folding Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Neutrophil Degranulation Protein Stabilization Chaperone Mediated Protein Folding Independent Of Cofactor Chaperone-mediated Protein Complex Assembly Positive Regulation Of Telomerase Activity ScaRNA Localization To Cajal Body Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways			Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Neutrophil degranulation Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Crohn's disease ( 23850713 23266558) Endometrial cancer (endometrioid histology) ( 30093612) Health literacy ( 31250787) Serum total protein level ( 29403010) Systemic lupus erythematosus ( 26663301)	Height ( 18391951) Logical memory (delayed recall) in normal cognition ( 29274321) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)
Interacting Genes		26 interacting genes: ABCF3 C2orf73 C9orf78 CASK CCDC158 CCDC85B CCT2 CFAP36 CHKA DAPP1 FAM9B HGS HSP90AB1 HSPA5 HTRA1 ITSN1 ITSN2 KIFC3 MSL1 MTUS2 PDE4DIP SH3BGR SRP72 VCPIP1 WAS WASL	18 interacting genes: ACTA1 ACTB EEF2 ERLIN2 ESR1 FCHSD2 HSP90AB1 HSP90B1 PRPF40A PSMC6 PSMD2 RPS3 SUMO4 TUBA1B VAV2 VRK2 YWHAG ZNRD2
Entrez ID		9873	10576
HPRD ID		13321	06895
Ensembl ID		ENSG00000137478	ENSG00000166226
Uniprot IDs		O94868	P78371 V9HW96
PDB IDs		2DL5 2DL7 6GBU	6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8
Enriched GO Terms of Interacting Partners?
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