GIT2 and EDC4

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		GIT2	EDC4
Description		GIT ArfGAP 2	enhancer of mRNA decapping 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Focal Adhesion	P-body Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity	Biological_process Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Pathways			mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolic syndrome ( 20694148) Metabolite levels ( 23823483) Metabolite levels (MHPG) ( 23319000)	HDL cholesterol ( 21347282) Metabolic syndrome ( 22399527) Schizophrenia ( 25056061 29483656)
Interacting Genes		44 interacting genes: ACTG1 ACTN1 ARHGEF7 ATF5 C4BPA CALCOCO2 CORO1A E2F2 EDC4 GCH1 GIT1 GRK2 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG	5 interacting genes: CCL5 EIF2AK2 FBLN1 GIT2 YTHDC1
Entrez ID		9815	23644
HPRD ID		09779	06911
Ensembl ID		ENSG00000139436	ENSG00000038358
Uniprot IDs		F8VXI9 F8W822 Q14161 Q68DM7 Q6FI58	Q6P2E9
PDB IDs
Enriched GO Terms of Interacting Partners?
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