DAZAP2 and EPN1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		DAZAP2	EPN1
Description		DAZ associated protein 2	epsin 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Nuclear Speck Protein-containing Complex	Nucleus Cytosol Plasma Membrane Clathrin-coated Pit
	Molecular Function	Protein Binding Receptor Tyrosine Kinase Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Identical Protein Binding Protein Serine/threonine Kinase Activator Activity WW Domain Binding	Protein Binding Lipid Binding
	Biological Process	Positive Regulation Of Protein Serine/threonine Kinase Activity	In Utero Embryonic Development Endocytosis Notch Signaling Pathway Female Pregnancy Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Embryonic Organ Development Membrane Organization Negative Regulation Of Sprouting Angiogenesis
Pathways			EGFR downregulation Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs			1,4-Diethylene Dioxide 1D-myo-inositol 1,4,5-trisphosphate
Diseases
GWAS			Major depressive disorder ( 23377640)
Interacting Genes		91 interacting genes: AATF ARID5A ATXN1 ATXN1L BAG3 BATF2 C1orf94 CALCOCO2 CCDC120 CDK4 CEP70 CLASRP COL4A2 COL4A5 CXCL12 DAB1 DAZ1 DAZL DCUN1D1 EPN1 EXD3 FAM168A FBN3 GPSM1 HGS HIP1 INCA1 KRTAP19-5 KRTAP8-1 LASP1 LMO2 MAGED1 MED31 NDUFA5 NEDD4 NEDD4L NOC4L NOTCH1 OPTN OTULIN PEF1 PLEKHB2 PLSCR1 POGZ POLI PRR20A RABGEF1 RBFOX1 RBFOX2 RBM11 RBPMS RHOXF2 RNF115 RNF208 ROR2 RPS27A SEPTIN2 SMAP2 SMURF2 SOX6 SQSTM1 STAM2 STAT6 TAX1BP1 TCF7L2 TENT5B TENT5C TEX37 TLE1 TNIP3 TOLLIP UBA52 UBAC1 UBASH3A UBASH3B UBB UBC UBE2D4 UBE2E2 UBE3A UBQLN4 USP5 VHLL VPS37C WDR73 WWP1 ZC3H10 ZFAND2B ZFYVE9 ZNF34 ZNF581	24 interacting genes: AP2A1 AP2A2 CDK1 CEP126 CLTC CRMP1 DAZAP2 EPS15 EPS15L1 FBXO25 HIP1R LAPTM5 MAP3K1 MED31 PLEKHB2 REPS2 RNF11 SCNN1A SCNN1B SCNN1G SMURF1 TFAP2A UBC ZBTB16
Entrez ID		9802	29924
HPRD ID		08463	06270
Ensembl ID		ENSG00000183283	ENSG00000063245
Uniprot IDs		A0A024R110 Q15038	A0A024R4S1 Q9Y6I3
PDB IDs			1INZ 1KYD
Enriched GO Terms of Interacting Partners?
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