IST1 and CAPN7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		IST1	CAPN7
Description		IST1 factor associated with ESCRT-III	calpain 7
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GO Annotations	Cellular Component	Chromatin Extracellular Region Nuclear Envelope Endoplasmic Reticulum-Golgi Intermediate Compartment Centrosome Cytosol Midbody Azurophil Granule Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome Flemming Body	Nucleus Extracellular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding Protein-containing Complex Binding Cadherin Binding MIT Domain Binding	Endopeptidase Activity Calcium-dependent Cysteine-type Endopeptidase Activity Protein Binding MIT Domain Binding
	Biological Process	Protein Localization Abscission Protein Transport Viral Release From Host Cell Multivesicular Body Assembly Neutrophil Degranulation Establishment Of Protein Localization Positive Regulation Of Proteolysis Viral Capsid Secondary Envelopment Positive Regulation Of Collateral Sprouting Cell Division Cytoskeleton-dependent Cytokinesis ESCRT III Complex Disassembly	Positive Regulation Of Epithelial Cell Migration Self Proteolysis
Pathways		Neutrophil degranulation Sealing of the nuclear envelope (NE) by ESCRT-III	Degradation of the extracellular matrix
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Intelligence (MTAG) ( 29326435) Response to anti-TNF therapy in rheumatoid arthritis ( 26776603)	Metabolite levels ( 23823483)
Interacting Genes		5 interacting genes: APEH ATXN1 CAPN7 SPAST UBQLN1	7 interacting genes: IST1 MDM4 TNFAIP1 UBL7 VHL ZBTB9 ZFYVE19
Entrez ID		9798	23473
HPRD ID		13784	05908
Ensembl ID		ENSG00000182149	ENSG00000131375
Uniprot IDs		B4DXC9 P53990	Q7Z479 Q9Y6W3
PDB IDs		3FRR 3FRS 3JC1 4U7E 4U7I 4U7Y 4WZX 6E8G	2QFE
Enriched GO Terms of Interacting Partners?
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