SNX17 and LDLR

  • Number of citations of the paper that reports this interaction (PubMedID 12169628)
  • 42
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro, in vivo)

SNX17

LDLR

Description sorting nexin 17 low density lipoprotein receptor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcohol use disorder (total score) ( 30336701)
  • Crohn's disease ( 28067908)
  • High light scatter reticulocyte count ( 27863252)
  • Inflammatory bowel disease ( 28067908)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Microalbuminuria ( 31511532)
  • Reticulocyte count ( 27863252)
  • Reticulocyte fraction of red cells ( 27863252)
  • Triglyceride levels ( 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Urinary albumin excretion ( 30220432)
  • Urinary albumin excretion (no hypertensive medication) ( 30220432)
  • Urinary albumin-to-creatinine ratio ( 31630189 30910378 31511532)
  • Urinary sodium to potassium ratio ( 30910378)
Interacting Genes 11 interacting genes: ANXA2 APP HRAS LDLR LRP1 LRP2 LRP8 RLIM SELP SKIL VLDLR 14 interacting genes: AP1M2 APOB APOE CD36 CREBBP DAB1 DAB2 HSPA5 LDLRAP1 LRPAP1 MAP4 PCSK9 PF4 SNX17
Entrez ID 9784 3949
HPRD ID 05812 06091
Ensembl ID ENSG00000115234 ENSG00000130164
Uniprot IDs B4DDM3 B4DQ37 B4DTB8 Q15036 A0A024R7D5 P01130
PDB IDs 3FOG 3LUI 4GXB 4TKN 1AJJ 1D2J 1F5Y 1F8Z 1HJ7 1HZ8 1I0U 1IJQ 1LDL 1LDR 1LRX 1N7D 1XFE 2FCW 2KRI 2LGP 2M7P 2MG9 2W2M 2W2N 2W2O 2W2P 2W2Q 3BPS 3GCW 3GCX 3M0C 3P5B 3P5C 3SO6 4NE9 5OY9 5OYL
Enriched GO Terms of Interacting Partners?
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