TBKBP1 and SKAP1

		TBKBP1	SKAP1
Description		TBK1 binding protein 1	src kinase associated phosphoprotein 1
Image		No pdb structure
GO Annotations	Cellular Component		Ruffle Immunological Synapse Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Microtubule Plus-end T Cell Receptor Complex Plasma Membrane Raft
	Molecular Function	Protein Binding Metal Ion Binding	SH3/SH2 Adaptor Activity Protein Binding SH3 Domain Binding Protein Kinase Binding Protein Phosphatase Binding SH2 Domain Binding Protein Homodimerization Activity Protein-containing Complex Binding Microtubule Plus-end Binding
	Biological Process	Viral Process Innate Immune Response	Microtubule Cytoskeleton Organization Positive Regulation Of Cell-matrix Adhesion Adaptive Immune Response Positive Regulation Of Adaptive Immune Response Positive Regulation Of Signal Transduction Cell Migration Positive Regulation Of Integrin Activation Positive Regulation Of Cell-cell Adhesion Mediated By Integrin Positive Regulation Of Heterotypic Cell-cell Adhesion Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II T Cell Receptor Signaling Pathway Cellular Response To Epidermal Growth Factor Stimulus Protein Localization To Plasma Membrane Positive Regulation Of Leukocyte Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 23749187 21743469) Asthma ( 31619474) Asthma (childhood onset) ( 31036433) Body mass index ( 26426971 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically inactive individuals ( 28448500) Multiple sclerosis ( 22190364) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)	Body mass index ( 28892062 25673413) Endometrial cancer ( 30093612) Endometrial cancer (endometrioid histology) ( 30093612) Epithelial ovarian cancer ( 25581431) Food allergy ( 29030101) Generalized epilepsy ( 22949513) Intelligence ( 28530673) Lean body mass ( 28552196) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Ovarian cancer ( 20852632) Peanut allergy ( 29030101) Pulse pressure ( 30578418)
Interacting Genes		5 interacting genes: AGO2 APBA3 CBX1 RB1CC1 SKAP1	15 interacting genes: APP BLCAP DYNLL2 ELOC FAM102A FYB1 FYN GRB2 LCK LYN PRAM1 PTPRC SH2D4A SRC TBKBP1
Entrez ID		9755	8631
HPRD ID		12239	05396
Ensembl ID		ENSG00000198933	ENSG00000141293
Uniprot IDs		A7MCY6	Q86WV1 V9HW03
PDB IDs			1U5D
Enriched GO Terms of Interacting Partners?
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