SKAP1 and FAM102A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SKAP1	FAM102A
Description		src kinase associated phosphoprotein 1	family with sequence similarity 102 member A
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Immunological Synapse Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Microtubule Plus-end T Cell Receptor Complex Plasma Membrane Raft
	Molecular Function	SH3/SH2 Adaptor Activity Protein Binding SH3 Domain Binding Protein Kinase Binding Protein Phosphatase Binding SH2 Domain Binding Protein Homodimerization Activity Protein-containing Complex Binding Microtubule Plus-end Binding	Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Positive Regulation Of Cell-matrix Adhesion Adaptive Immune Response Positive Regulation Of Adaptive Immune Response Positive Regulation Of Signal Transduction Cell Migration Positive Regulation Of Integrin Activation Positive Regulation Of Cell-cell Adhesion Mediated By Integrin Positive Regulation Of Heterotypic Cell-cell Adhesion Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II T Cell Receptor Signaling Pathway Cellular Response To Epidermal Growth Factor Stimulus Protein Localization To Plasma Membrane Positive Regulation Of Leukocyte Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28892062 25673413) Endometrial cancer ( 30093612) Endometrial cancer (endometrioid histology) ( 30093612) Epithelial ovarian cancer ( 25581431) Food allergy ( 29030101) Generalized epilepsy ( 22949513) Intelligence ( 28530673) Lean body mass ( 28552196) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Ovarian cancer ( 20852632) Peanut allergy ( 29030101) Pulse pressure ( 30578418)	Albumin-globulin ratio ( 29403010) Body mass index ( 26426971) Glaucoma (primary angle closure) ( 27064256) Monocyte count ( 29403010) Urate levels ( 31578528)
Interacting Genes		15 interacting genes: APP BLCAP DYNLL2 ELOC FAM102A FYB1 FYN GRB2 LCK LYN PRAM1 PTPRC SH2D4A SRC TBKBP1	4 interacting genes: ENKD1 SH3GL1 SKAP1 SKAP2
Entrez ID		8631	399665
HPRD ID		05396	13262
Ensembl ID		ENSG00000141293	ENSG00000167106
Uniprot IDs		Q86WV1 V9HW03	Q5T9C2
PDB IDs		1U5D
Enriched GO Terms of Interacting Partners?
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