CD81 and PTGFRN

Number of citations of the paper that reports this interaction (PubMedID 11278880)
67

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo, in vitro)

		CD81	PTGFRN
Description		CD81 molecule	prostaglandin F2 receptor inhibitor
Image			No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane Integral Component Of Membrane Basolateral Plasma Membrane Vesicle Extracellular Exosome Tetraspanin-enriched Microdomain	Endoplasmic Reticulum Membrane Golgi Apparatus Cell Surface Integral Component Of Membrane
	Molecular Function	Virus Receptor Activity Integrin Binding Protein Binding Cholesterol Binding MHC Class II Protein Complex Binding MHC Class II Protein Binding Transferrin Receptor Binding	Protein Binding
	Biological Process	Activation Of MAPK Activity Immunological Synapse Formation Humoral Immune Response Mediated By Circulating Immunoglobulin Positive Regulation Of Inflammatory Response To Antigenic Stimulus Protein Localization Positive Regulation Of Cell Proliferation Myoblast Fusion Involved In Skeletal Muscle Regeneration Regulation Of Complement Activation Positive Regulation Of B Cell Proliferation Receptor Internalization Regulation Of Protein Stability Macrophage Fusion CD4-positive, Alpha-beta T Cell Costimulation Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Positive Regulation Of Transcription By RNA Polymerase II Viral Entry Into Host Cell Receptor-mediated Virion Attachment To Host Cell Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Immune Response Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of T Cell Receptor Signaling Pathway Protein Localization To Lysosome Positive Regulation Of Protein Exit From Endoplasmic Reticulum Cellular Response To Low-density Lipoprotein Particle Stimulus Protein Localization To Plasma Membrane Osteoclast Fusion Positive Regulation Of Receptor Clustering Positive Regulation Of Protein Catabolic Process In The Vacuole Regulation Of Macrophage Migration Positive Regulation Of Adaptive Immune Memory Response Positive Regulation Of T-helper 2 Cell Cytokine Production Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell	Myoblast Fusion Involved In Skeletal Muscle Regeneration Lipid Droplet Organization
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Regulation of Complement cascade
Drugs
Diseases
GWAS			Blood protein levels ( 30072576 29875488) Erectile dysfunction and prostate cancer treatment ( 20932654) Low susceptibility to hepatitis C infection ( 31206233) Type 2 diabetes ( 30054458 30297969)
Interacting Genes		23 interacting genes: ADRB2 CD19 CD9 CSNK2B DLG5 GLP1R HNRNPD IFITM1 IGSF8 INO80B ITGA4 JAK3 KIT LMNA MYOC PTGFRN RBBP6 RNF128 SHC1 SIRPA TSPAN4 VKORC1 ZBTB16	5 interacting genes: CD151 CD63 CD81 CD82 CD9
Entrez ID		975	5738
HPRD ID		08924	03124
Ensembl ID		ENSG00000110651	ENSG00000134247
Uniprot IDs		A0A024RCB7 E9PJK1 P60033	Q9P2B2
PDB IDs		1G8Q 1IV5 2AVZ 3X0E 5DFV 5DFW 5M2C 5M33 5M3D 5M3T 5M4R 5TCX 6EJG 6EJM 6EK2
Enriched GO Terms of Interacting Partners?
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