SECISBP2L and DYNLL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SECISBP2L	DYNLL2
Description		SECIS binding protein 2 like	dynein light chain LC8-type 2
Image		No pdb structure
GO Annotations	Cellular Component	Ribonucleoprotein Complex	Nucleus Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Plasma Membrane Cilium Postsynaptic Density Membrane Dynein Complex Myosin V Complex Ciliary Tip Postsynapse Glutamatergic Synapse
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding Selenocysteine Insertion Sequence Binding Ribonucleoprotein Complex Binding	Protein Binding Identical Protein Binding Protein-containing Complex Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding Scaffold Protein Binding
	Biological Process	Selenocysteine Incorporation	ER To Golgi Vesicle-mediated Transport Macroautophagy Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Intraciliary Transport Involved In Cilium Assembly Positive Regulation Of ATP-dependent Microtubule Motor Activity, Plus-end-directed
Pathways			Activation of BMF and translocation to mitochondria Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Macroautophagy MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) Intraflagellar transport RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Lung adenocarcinoma ( 28604730 31326317) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Weight ( 28552196)	Blood protein levels ( 30072576)
Interacting Genes		3 interacting genes: DYNLL2 FBN1 SASH1	21 interacting genes: BCL2L11 BMF C12orf40 DLGAP1 DNAL4 DYNC1I1 EWSR1 GPHN GPRIN2 HMBOX1 HOMER3 IHO1 MEOX2 MORN3 MYO5A PAK1 RASGRP3 SECISBP2L SKAP1 THAP10 XIAP
Entrez ID		9728	140735
HPRD ID		17181	06489
Ensembl ID		ENSG00000138593	ENSG00000264364
Uniprot IDs		A0A024R5R0 Q93073	Q96FJ2
PDB IDs			2XQQ 3P8M 4D07
Enriched GO Terms of Interacting Partners?
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