MDC1 and H2AX

  • Number of citations of the paper that reports this interaction (PubMedID 12607005)
  • 302
  • Data Source:
  • HPRD (in vivo)

MDC1

H2AX

Description mediator of DNA damage checkpoint 1 H2A.X variant histone
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 39 interacting genes: ANAPC1 ATM BARD1 BRCA1 CASP3 CENPC CHEK2 COPS5 CREBBP CSNK2A1 DTX2 EP300 GATA4 H2AX HDAC10 HDAC8 HINFP NBN NCL NSD2 PIAS1 PIAS4 PRIM1 RAD50 RAD51 RNF8 SMC1A SRPK2 SUMO2 TNKS2 TP53 TP53BP1 UIMC1 USP13 USP15 USP28 VAMP5 WRN ZNF251 47 interacting genes: A2M ACTB ALG9 ATM ATR BARD1 BMI1 BRCA1 BRCA2 BRD1 CALM1 COPG1 DDX21 DHX9 EYA1 HUWE1 KAT5 MASP1 MDC1 MRE11 NBN NCL NGFR OTUB1 PAXIP1 PBK PPP1CA PRKDC PTPA QARS1 RNF168 RNF8 RPS6KA3 SMARCA4 SSRP1 SUPT16H SUPT5H TAF1C TAF5L TERF2 TIAM2 TOPORS TP53BP1 TRAF6 TSSK6 USP11 WRN
Entrez ID 9656 3014
HPRD ID 16252 03465
Ensembl ID ENSG00000137337 ENSG00000188486
Uniprot IDs A0A1U9XBC1 A1Z5I9 Q14676 P16104
PDB IDs 2ADO 2AZM 2ETX 3K05 3UEO 3UMZ 3UN0 3UNM 3UNN 3UOT 1YDP 2AZM 2D31 2DYP 3SHV 3SQD 3SZM 3U3Z
Enriched GO Terms of Interacting Partners?
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