H2AX and TIAM2

  • Number of citations of the paper that reports this interaction (PubMedID 21900206)
  • 114
  • Data Source:
  • BioGRID (two hybrid)

H2AX

TIAM2

Description H2A.X variant histone TIAM Rac1 associated GEF 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction) ( 28560309)
  • Asthma ( 31361310)
  • Dimensional psychopathology (Arousal) ( 29496196)
  • Dimensional psychopathology (Negative) ( 29496196)
  • Heel bone mineral density ( 30598549)
  • Lipoprotein (a) levels ( 26377243)
  • Triiodothyronine levels and thyroxine levels ( 30843173)
Interacting Genes 47 interacting genes: A2M ACTB ALG9 ATM ATR BARD1 BMI1 BRCA1 BRCA2 BRD1 CALM1 COPG1 DDX21 DHX9 EYA1 HUWE1 KAT5 MASP1 MDC1 MRE11 NBN NCL NGFR OTUB1 PAXIP1 PBK PPP1CA PRKDC PTPA QARS1 RNF168 RNF8 RPS6KA3 SMARCA4 SSRP1 SUPT16H SUPT5H TAF1C TAF5L TERF2 TIAM2 TOPORS TP53BP1 TRAF6 TSSK6 USP11 WRN 9 interacting genes: ANXA7 DISC1 DNM2 H2AX PARD3 SH3GL2 TK1 TNIK UFD1
Entrez ID 3014 26230
HPRD ID 03465 05273
Ensembl ID ENSG00000188486 ENSG00000146426
Uniprot IDs P16104 B3KW11 Q8IVF5
PDB IDs 1YDP 2AZM 2D31 2DYP 3SHV 3SQD 3SZM 3U3Z
Enriched GO Terms of Interacting Partners?
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