PPM1F and MARS1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		PPM1F	MARS1
Description		protein phosphatase, Mg2+/Mn2+ dependent 1F	methionyl-tRNA synthetase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Protein-containing Complex Perinuclear Region Of Cytoplasm	Nucleolus Cytoplasm Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex Extracellular Exosome
	Molecular Function	Protein Serine/threonine Phosphatase Activity Magnesium-dependent Protein Serine/threonine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Calmodulin-dependent Protein Phosphatase Activity Metal Ion Binding	TRNA Binding Methionine-tRNA Ligase Activity ATP Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Positive Regulation Of Gene Expression Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cell-substrate Adhesion Histone Dephosphorylation Positive Regulation Of Cell Migration Negative Regulation Of Peptidyl-serine Phosphorylation Cellular Response To Drug Peptidyl-threonine Dephosphorylation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Growth Positive Regulation Of Chemotaxis Negative Regulation Of Protein Transport Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Peptidyl-serine Dephosphorylation Intrinsic Apoptotic Signaling Pathway Regulation Of Cellular Protein Localization Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin	TRNA Aminoacylation For Protein Translation Methionyl-tRNA Aminoacylation Cellular Response To Starvation RRNA Transcription Cellular Response To Insulin Stimulus Cellular Response To Platelet-derived Growth Factor Stimulus Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
Pathways		Negative regulation of NMDA receptor-mediated neuronal transmission	Selenoamino acid metabolism Cytosolic tRNA aminoacylation
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Attention deficit hyperactivity disorder ( 18839057) Bipolar disorder ( 31043756)
Interacting Genes		17 interacting genes: AATK ARHGEF7 CAMK2A ERBB2 ERBB3 ERBB4 FAM161A FEM1A FEM1B LATS1 LMTK2 MARS1 PAK1 PRKAA1 PTK7 ROR1 ROR2	8 interacting genes: CASK ESR1 HNRNPUL1 MAFK MAPK14 PPM1F RPS27 TNNT1
Entrez ID		9647	4141
HPRD ID		10163	08864
Ensembl ID		ENSG00000100034	ENSG00000166986
Uniprot IDs		B5MCT7 P49593	P56192
PDB IDs			2DJV 4BL7 4BVX 4BVY 5GL7 5GOY 5Y6L
Enriched GO Terms of Interacting Partners?
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