MARS1 and CASK

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		MARS1	CASK
Description		methionyl-tRNA synthetase 1	calcium/calmodulin dependent serine protein kinase
Image
GO Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex Extracellular Exosome	Basement Membrane Nuclear Lamina Nucleolus Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Actin Cytoskeleton Basolateral Plasma Membrane Nuclear Matrix Vesicle Presynaptic Membrane Ciliary Membrane Schaffer Collateral - CA1 Synapse
	Molecular Function	TRNA Binding Methionine-tRNA Ligase Activity ATP Binding	Guanylate Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding Calmodulin Binding ATP Binding Neurexin Family Protein Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Methionyl-tRNA Aminoacylation Cellular Response To Starvation RRNA Transcription Cellular Response To Insulin Stimulus Cellular Response To Platelet-derived Growth Factor Stimulus Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I	Negative Regulation Of Cell-matrix Adhesion Protein Phosphorylation Cell Adhesion Neurotransmitter Secretion Negative Regulation Of Keratinocyte Proliferation Positive Regulation Of Transcription By RNA Polymerase II GMP Metabolic Process GDP Metabolic Process Negative Regulation Of Wound Healing Calcium Ion Import Positive Regulation Of Calcium Ion Import Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Synaptic Vesicle Exocytosis
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation	Dopamine Neurotransmitter Release Cycle Syndecan interactions Nephrin family interactions Neurexins and neuroligins Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs			Formic Acid
Diseases			FG syndrome (FGS); Opitz-Kaveggia syndrome
GWAS
Interacting Genes		8 interacting genes: CASK ESR1 HNRNPUL1 MAFK MAPK14 PPM1F RPS27 TNNT1	85 interacting genes: AKAP9 APBA1 ATP2B4 BNIP3L CADM1 CASKIN1 CDK9 CNTNAP2 CNTNAP4 DDX54 DLG1 DLG4 DNAJC5 DUSP3 ELL2 EPB41 EPS8 ERBIN F11R FCHSD2 FMR1 GCNT3 GLS2 GRIK2 GRIN2A GTSE1 HGS ID1 IL15RA IL18 KCNA4 KCNJ12 KCNJ2 KCNJ4 KIF2A KLC4 LIN7A LIN7B MAPRE1 MAPRE2 MARK2 MARS1 MED1 MLLT6 NDEL1 NPHS1 NRXN1 NRXN2 NRXN3 P2RX7 PARD3B PARD6G PCBP2 PCM1 PKP2 PLK2 PPP4R3A PRC1 PRKCI PRKD2 PRKN PRPF3 PTGS2 RAB3A RBBP6 RBM10 RBM14 RBM5 RPA2 RPH3A SDC1 SDC2 SDC3 SDC4 SF3B2 SH2D4A SLAIN2 SRPK2 TANC1 TBR1 TRIM22 TSPYL2 WHRN WNT7B YWHAE
Entrez ID		4141	8573
HPRD ID		08864	02164
Ensembl ID		ENSG00000166986	ENSG00000147044
Uniprot IDs		P56192	A0A2R8Y6F8 A0A2R8YE77 O14936
PDB IDs		2DJV 4BL7 4BVX 4BVY 5GL7 5GOY 5Y6L	1KGD 1KWA 1ZL8 3C0G 3C0H 3C0I 3MFR 3MFS 3MFT 3MFU 3TAC
Enriched GO Terms of Interacting Partners?
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