APBA3 and ARF4

Number of citations of the paper that reports this interaction (PubMedID 12842896)
38

Data Source:
BioGRID (two hybrid)

		APBA3	ARF4
Description		amyloid beta precursor protein binding family A member 3	ADP ribosylation factor 4
Image
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Dendritic Spine Synapse Perinuclear Region Of Cytoplasm	Cytoplasm Golgi Apparatus Cytosol Membrane Ruffle Membrane Dendritic Spine Extracellular Exosome Glutamatergic Synapse
	Molecular Function	Amyloid-beta Binding Enzyme Inhibitor Activity Protein Binding Enzyme Binding	GTPase Activity ARF Guanyl-nucleotide Exchange Factor Activity Epidermal Growth Factor Receptor Binding Protein Binding GTP Binding
	Biological Process	In Utero Embryonic Development Chemical Synaptic Transmission Regulation Of Gene Expression Protein Transport Negative Regulation Of Catalytic Activity	Protein ADP-ribosylation Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Epidermal Growth Factor Receptor Signaling Pathway Brain Development Learning Vesicle-mediated Transport Cell Migration Activation Of Phospholipase D Activity Negative Regulation Of Apoptotic Process Apical Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Transcription By RNA Polymerase II Response To Axon Injury Dendritic Spine Development Protein Localization To Cilium Regulation Of Postsynapse Organization Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Neurexins and neuroligins	VxPx cargo-targeting to cilium VxPx cargo-targeting to cilium COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs			Guanosine-5'-Diphosphate
Diseases
GWAS
Interacting Genes		8 interacting genes: APP ARF3 ARF4 AZI2 BCR EGFR TANK TBKBP1	13 interacting genes: ADRB2 APBA1 APBA2 APBA3 EGFR HNRNPD IKBKG PTEN RAB11FIP3 RCHY1 RHOA SDCBP2 SIRPA
Entrez ID		9546	378
HPRD ID		05038	03107
Ensembl ID		ENSG00000011132	ENSG00000168374
Uniprot IDs		O96018	P18085
PDB IDs		2YT7 2YT8 5UWS	1Z6X
Enriched GO Terms of Interacting Partners?
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