STX8 and COPA

Number of citations of the paper that reports this interaction (PubMedID 12388752)
47

Data Source:
HPRD (in vivo)

		STX8	COPA
Description		syntaxin 8	COPI coat complex subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Early Endosome Late Endosome Endoplasmic Reticulum Trans-Golgi Network Cytosol Integral Component Of Plasma Membrane Endomembrane System Integral Component Of Membrane SNARE Complex Late Endosome Membrane Vesicle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome	Golgi Membrane Extracellular Space Cytoplasm Endoplasmic Reticulum Membrane Cytosol Membrane COPI Vesicle Coat Transport Vesicle Growth Cone Extracellular Exosome
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity Syntaxin Binding Ubiquitin Protein Ligase Binding	MRNA Binding Hormone Activity Structural Molecule Activity
	Biological Process	Intracellular Protein Transport Vesicle Fusion Endosome To Lysosome Transport Early Endosome To Late Endosome Transport Vesicle Docking Cellular Response To Interferon-gamma Regulation Of Protein Localization To Plasma Membrane	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Signal Transduction Pancreatic Juice Secretion Protein Localization To Axon Protein Localization To Cell Leading Edge
Pathways			COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Borderline personality disorder ( 28632202) HDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507)	Breast size ( 27182965)
Interacting Genes		18 interacting genes: ACVR1 AQP2 CALM1 CLN8 COPA CREB3 LMNA NAPA NAPG NSF STX1A STX4 STX7 TGFBR1 VPS11 VPS18 VTI1B WDR91	14 interacting genes: ARCN1 ARFGAP1 COPB2 COPE MTNR1B PDGFRB SACM1L SCYL1 SLC25A11 STX8 TMED10 TMED2 WBP1 WBP2
Entrez ID		9482	1314
HPRD ID		05012	03564
Ensembl ID		ENSG00000170310	ENSG00000122218
Uniprot IDs		Q9UNK0	P53621
PDB IDs			6PBG 6TZT 6U3V
Enriched GO Terms of Interacting Partners?
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