COPA and SACM1L

Number of citations of the paper that reports this interaction (PubMedID 14527956)
42

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		COPA	SACM1L
Description		COPI coat complex subunit alpha	SAC1 like phosphatidylinositide phosphatase
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Space Cytoplasm Endoplasmic Reticulum Membrane Cytosol Membrane COPI Vesicle Coat Transport Vesicle Growth Cone Extracellular Exosome	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	MRNA Binding Hormone Activity Structural Molecule Activity	Phosphatidylinositol-3-phosphatase Activity Protein Binding Phosphatase Activity Phosphatidylinositol Phosphate 4-phosphatase Activity Phosphatidylinositol-4-phosphate Phosphatase Activity
	Biological Process	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Signal Transduction Pancreatic Juice Secretion Protein Localization To Axon Protein Localization To Cell Leading Edge	Phosphatidylinositol Biosynthetic Process Phosphatidylinositol Dephosphorylation
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	Synthesis of PIPs at the ER membrane Synthesis of PIPs at the Golgi membrane
Drugs
Diseases
GWAS		Breast size ( 27182965)	Acne (severe) ( 24927181) Response to anti-depressant treatment in major depressive disorder ( 22041458)
Interacting Genes		14 interacting genes: ARCN1 ARFGAP1 COPB2 COPE MTNR1B PDGFRB SACM1L SCYL1 SLC25A11 STX8 TMED10 TMED2 WBP1 WBP2	6 interacting genes: COPA COPB2 COPG1 CREB3 LMNA PRKCA
Entrez ID		1314	22908
HPRD ID		03564	07587
Ensembl ID		ENSG00000122218	ENSG00000211456
Uniprot IDs		P53621	B4DVV3 E9PGZ4 Q9NTJ5
PDB IDs		6PBG 6TZT 6U3V
Enriched GO Terms of Interacting Partners?
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