MAPK8IP1 and ARHGEF28

  • Number of citations of the paper that reports this interaction (PubMedID 10574993)
  • 29
  • Data Source:
  • HPRD (two hybrid, in vivo, in vitro)

MAPK8IP1

ARHGEF28

Description mitogen-activated protein kinase 8 interacting protein 1 Rho guanine nucleotide exchange factor 28
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717)
  • Axial length ( 24144296)
  • Chin dimples ( 27182965)
  • HDL cholesterol ( 30275531)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes 27 interacting genes: AKT1 APP ARHGEF28 DUSP16 EGFR ERBB2 EXOSC8 KLC1 LRP1 LRP2 LRP8 MAP2K7 MAP3K10 MAP3K11 MAP3K12 MAP3K13 MAP3K7 MAPK8 MAPK8IP2 MAPK8IP3 MAPK9 PARK7 PAX2 RECQL5 SNCA TIAM1 VRK2 4 interacting genes: MAPK8IP1 RHOA YWHAE YWHAH
Entrez ID 9479 64283
HPRD ID 05223 15244
Ensembl ID ENSG00000121653 ENSG00000214944
Uniprot IDs Q6NUQ9 Q9UQF2 Q8N1W1
PDB IDs 2G01 2GMX 2H96 3OXI 3PTG 3VUD 3VUG 3VUH 3VUI 3VUK 3VUL 3VUM 4E73 4G1W 4H39 4HYS 4HYU 4IZY 5LW1 6FUZ 6BC0 6BC1
Enriched GO Terms of Interacting Partners?
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