MED7 and MED8

Number of citations of the paper that reports this interaction (PubMedID 12584197)
20

Data Source:
HPRD (in vitro)

		MED7	MED8
Description		mediator complex subunit 7	mediator complex subunit 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleoplasm Transcription Factor Complex Mediator Complex Nuclear Body	Nucleoplasm Mediator Complex Core Mediator Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding Ubiquitin Protein Ligase Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Coregulator Activity Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Stem Cell Population Maintenance Positive Regulation Of Nucleic Acid-templated Transcription	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Medication use (thyroid preparations) ( 31015401)	Feeling worry ( 29500382) Schizophrenia ( 28991256)
Interacting Genes		22 interacting genes: CTDP1 DNMT3L ESR1 ESR2 HAUS1 HGS HNF4A IKBKG LZTR1 MED31 MED8 MED9 PCBD2 PML RBFOX2 RELA RHOXF2 SREBF1 TRIM15 TRIM29 UBE2I ZSCAN1	31 interacting genes: APP ARRB2 CCNC CDK8 CTDP1 ELOC HSPB3 KRT40 MED1 MED11 MED12 MED17 MED19 MED20 MED22 MED25 MED26 MED27 MED28 MED30 MED31 MED6 MED7 MED9 PEX14 PHYHIP PNMA1 SNTA1 THOC7 UBALD1 USP49
Entrez ID		9443	112950
HPRD ID		05439	06991
Ensembl ID		ENSG00000155868	ENSG00000159479
Uniprot IDs		O43513 Q6IAZ5	Q96G25
PDB IDs
Enriched GO Terms of Interacting Partners?
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