MED21 and SSC5D

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MED21	SSC5D
Description		mediator complex subunit 21	scavenger receptor cysteine rich family member with 5 domains
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Mediator Complex	Extracellular Space Cytoplasm Membrane Collagen-containing Extracellular Matrix
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Ubiquitin Protein Ligase Activity	Fibronectin Binding Scavenger Receptor Activity Protein Binding Laminin Binding Extracellular Matrix Binding
	Biological Process	Blastocyst Development Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination Stem Cell Population Maintenance RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II	Endocytosis Multicellular Organism Development Detection Of Bacterial Lipoprotein Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Negative Regulation Of Interleukin-8 Secretion
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Scavenging by Class B Receptors
Drugs
Diseases
GWAS		Dimensional psychopathology (Social) ( 29496196)	Height ( 28552196) Lung adenocarcinoma ( 28604730)
Interacting Genes		26 interacting genes: BLOC1S6 BRCA1 BTF3 CDK8 CDK9 ELOA ESR1 ESR2 HNF4A HTT MAGEA6 MAGEB4 MED29 PCBD2 POLR2A SKP1 SSC5D TARBP2 TFG THRA THRB TP53 TRIM27 VAV2 ZNF655 ZSCAN1	8 interacting genes: CEP170P1 DTNBP1 EXOC7 MED21 NECAB2 NUP62 SEC23IP TRAF1
Entrez ID		9412	284297
HPRD ID		09156	11444
Ensembl ID		ENSG00000152944	ENSG00000179954
Uniprot IDs		A0A024RAW0 Q13503	A1L4H1
PDB IDs
Enriched GO Terms of Interacting Partners?
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