PPIG and KCTD6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PPIG	KCTD6
Description		peptidylprolyl isomerase G	potassium channel tetramerization domain containing 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Nuclear Matrix Nuclear Speck	Cytosol M Band
	Molecular Function	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Unfolded Protein Binding	Protein Binding Ankyrin Binding Identical Protein Binding Cullin Family Protein Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization RNA Splicing Protein Refolding	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Growth Post-translational Protein Modification Negative Regulation Of Smoothened Signaling Pathway Protein Homooligomerization
Pathways			RUNX1 regulates estrogen receptor mediated transcription Neddylation Estrogen-dependent gene expression Antigen processing: Ubiquitination & Proteasome degradation
Drugs		L-Proline
Diseases
GWAS			Hepcidin/transferrin saturation ratio ( 27846281) Systemic lupus erythematosus ( 28714469) vWF levels ( 30586737)
Interacting Genes		26 interacting genes: BEND7 CACNA1A CEP70 CLK1 DAB1 DACH1 FHL3 KCTD6 LGALS3 NKAP PCBP1 PNMA2 PNN POLR2A PPCDC PRPF38A PRPF40A RBM39 SLU7 SMN1 SMN2 SP1 TFCP2 THAP1 YWHAG ZCCHC10	17 interacting genes: ACTN1 ACTN3 ANK1 C8orf33 CDC23 CTNND1 EHHADH FAM124B GOLGA8EP GOLGA8F GRB7 GSDMD LNX1 PPIG PRPF31 SDCBP ZCCHC10
Entrez ID		9360	200845
HPRD ID		12083	13769
Ensembl ID		ENSG00000138398	ENSG00000168301
Uniprot IDs		Q13427	Q8NC69
PDB IDs		2GW2 2WFI 2WFJ 5YZG
Enriched GO Terms of Interacting Partners?
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