RPL23 and EPS8L2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		RPL23	EPS8L2
Description		ribosomal protein L23	EPS8 like 2
Image
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Cytosol Ribosome Focal Adhesion Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Protein-containing Complex Extracellular Exosome	Cytosol Plasma Membrane Vesicle Stereocilium Bundle Stereocilium Tip Ruffle Membrane Protein-containing Complex Extracellular Exosome
	Molecular Function	Transcription Coactivator Binding RNA Binding Structural Constituent Of Ribosome Protein Binding Ubiquitin Protein Ligase Binding Large Ribosomal Subunit RRNA Binding Ubiquitin Ligase Inhibitor Activity	Actin Binding Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding Rac Guanyl-nucleotide Exchange Factor Activity Cadherin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Ribosomal Protein Import Into Nucleus SRP-dependent Cotranslational Protein Targeting To Membrane Positive Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Viral Transcription Protein-DNA Complex Disassembly Protein Stabilization Negative Regulation Of Cell Cycle Arrest Positive Regulation Of Cell Cycle Arrest Cellular Response To Actinomycin D Positive Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Ubiquitin Protein Ligase Activity Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process	Rho Protein Signal Transduction Sensory Perception Of Sound Regulation Of Rho Protein Signal Transduction Positive Regulation Of Ruffle Assembly
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		Alpha-Hydroxy-Beta-Phenyl-Propionic Acid Anisomycin Puromycin
Diseases
GWAS		Chronic obstructive pulmonary disease ( 30804561)
Interacting Genes		10 interacting genes: APP BCCIP CDC42 CLU DAPP1 EPS8L2 GRWD1 IPO5 PTEN RELA	7 interacting genes: APP PTK2 RIN3 RPL23 SASH1 SOS1 TNS2
Entrez ID		9349	64787
HPRD ID		04716	10940
Ensembl ID		ENSG00000125691	ENSG00000177106
Uniprot IDs		A0A024R1Q8 P62829	Q9H6S3
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6QZP	1WWU 1WXB
Enriched GO Terms of Interacting Partners?
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