RPL23 and IPO5

Number of citations of the paper that reports this interaction (PubMedID 9114010)
43

Data Source:
HPRD (in vitro)

		RPL23	IPO5
Description		ribosomal protein L23	importin 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Cytosol Ribosome Focal Adhesion Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Protein-containing Complex Extracellular Exosome	Nucleus Nuclear Pore Nucleolus Cytoplasm Membrane
	Molecular Function	Transcription Coactivator Binding RNA Binding Structural Constituent Of Ribosome Protein Binding Ubiquitin Protein Ligase Binding Large Ribosomal Subunit RRNA Binding Ubiquitin Ligase Inhibitor Activity	RNA Binding GTPase Inhibitor Activity Protein Binding Nuclear Localization Sequence Binding Ran GTPase Binding Nuclear Import Signal Receptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Ribosomal Protein Import Into Nucleus SRP-dependent Cotranslational Protein Targeting To Membrane Positive Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Viral Transcription Protein-DNA Complex Disassembly Protein Stabilization Negative Regulation Of Cell Cycle Arrest Positive Regulation Of Cell Cycle Arrest Cellular Response To Actinomycin D Positive Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Ubiquitin Protein Ligase Activity Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process	Protein Import Into Nucleus NLS-bearing Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus Viral Process Negative Regulation Of GTPase Activity Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Response To Amino Acid Stimulus
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	vRNP Assembly
Drugs		Alpha-Hydroxy-Beta-Phenyl-Propionic Acid Anisomycin Puromycin
Diseases
GWAS		Chronic obstructive pulmonary disease ( 30804561)	Peripheral artery disease ( 26488411) Smooth-surface caries ( 24556642)
Interacting Genes		10 interacting genes: APP BCCIP CDC42 CLU DAPP1 EPS8L2 GRWD1 IPO5 PTEN RELA	23 interacting genes: ACD BHLHB9 DPPA3 DTNBP1 H1-0 NUP153 NUP214 NUP62 NUP98 RAG2 RAN RANBP2 RPL13 RPL23 RPL23A RPL5 RPL7 RPS7 SRP19 SUMO2 TERF1 TINF2 WASL
Entrez ID		9349	3843
HPRD ID		04716	03597
Ensembl ID		ENSG00000125691	ENSG00000065150
Uniprot IDs		A0A024R1Q8 P62829	B3KWG6 O00410 Q9BVS9
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6QZP
Enriched GO Terms of Interacting Partners?
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